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方案
>99% (TLC)
表单
oil
分子量
300.43 g/mol
包装
pkg of 10 × 0.1 g (with screw cap (850530O-1g))
pkg of 2 × 100 mg (with screw cap (850530O-200mg))
pkg of 5 × 100 mg (with screw cap (850530O-500mg))
制造商/商品名称
Avanti Research™ - A Croda Brand 850530O
技术
protein sequencing: suitable
运输
dry ice
储存温度
−20°C
一般描述
单酰甘油（MAG）是甘油酯。7.7 MAG有14个碳酰基链，双层厚度为25.8Å。
这种新的脂质洗涤剂可用于利用脂质中间相结晶膜蛋白。该方法在不同方面被称为脂质立方相或细观法。该方法已被证明是相当通用的，因为它已被用于解析原核和真核蛋白质的 X 射线晶体学结构，即单体、同源和异源多聚体、含生色团和无生色团的蛋白质，以及 α 螺旋和 β 桶蛋白质。
应用
7.7 MAG可用作MdfA（多药转运蛋白）-YN1074（Fab片段）复合物中的宿主脂质，用于通过脂质立方相（LCP）法进行结晶。
生化/生理作用
单酰甘油（MAG）在食品工业中可用作乳化剂。7.7 MAG参与一种外膜蛋白BtuB（维生素B12转运蛋白）的介晶结晶。它还有助于助溶菌酶晶体生长。7.7 MAG在衍射级晶体的生长中也起着关键作用。MAG在制药和食品行业中有重要意义。
包装
5 mL 带螺旋盖的 PTFE 瓶 (850530O-1g)
5 mL 带螺旋盖的 PTFE 瓶 (850530O-200mg)
5 mL 带螺旋盖的 PTFE 瓶 (850530O-500mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Protein
Johner N, et al.
Journal of the American Chemical Society, 136, 3271-3271 (2014)
Kai Yu Chen et al.
Journal of agricultural and food chemistry, 67(29), 8191-8196 (2019-07-10)
Conversion of free fatty acids into monoacylglycerol gives rise to new structural properties, particularly amphipathic property. Therefore, monoacylglycerols are widely used in pharmaceutical and food industries and are also reported to facilitate better absorption into the human body. A functional
Lisa V Misquitta et al.
Structure (London, England : 1993), 12(12), 2113-2124 (2004-12-04)
Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms long. We hypothesized that a shorter-chained lipid producing a thinner bilayer would facilitate the
Kumar Nagarathinam et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 7), 423-430 (2017-07-12)
The active efflux of antibiotics by multidrug-resistance (MDR) transporters is a major pathway of drug resistance and complicates the clinical treatment of bacterial infections. MdfA is a member of the major facilitator superfamily (MFS) from Escherichia coli and provides resistance
Dianfan Li et al.
Crystal growth & design, 11(2), 530-537 (2011-07-12)
The default lipid for the bulk of the crystallogenesis studies performed to date using the cubic mesophase method is monoolein. There is no good reason however, why this 18-carbon, cis-monounsaturated monoacylglycerol should be the preferred lipid for all target membrane
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