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Merck
CN

850520P

Avanti

正十二烷基β--D-麦芽糖苷(DDM)

Avanti Research - A Croda Brand

别名:

DDM; 月桂基麦芽糖苷; 十二烷基4-O-α-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷

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About This Item

经验公式(希尔记法):
C24H46O11
CAS号:
分子量:
510.62
UNSPSC代码:
12161902
NACRES:
NA.25

描述

n-dodecyl-β-D-maltopyranoside

检测方案

>99% (contains <2% alpha isomer, TLC)

形式

powder

分子量

510.62 g/mol

包装

pkg of 1 × 1 g (850520P-1g)
pkg of 1 × 25 g (850520P-25g)
pkg of 1 × 5 g (850520P-5g)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

SMILES字符串

OC[C@H]1O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

InChI key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

一般描述

正十二烷基β-D-麦芽糖苷(DDM)是一种糖基表面活性剂。
DDM 是用于 GPCR 分离和纯化的使用最广泛的洗涤剂。 此外,LacY 可能有利于较高能量的原位中间周质开放构象,但在纯化后在 DDM 中塌陷为较低能量的周质闭合构象。有趣的是,支链麦芽糖苷洗涤剂可使嵌入膜的 LacY保持稳定。

应用

十二烷基-β-D-麦芽糖苷(DDM)已用于溶解成纤维细胞的线粒体提取物,从而对组装的氧化磷酸化(OXPHOS) 复合物进行一维蓝绿温和胶凝胶电泳(BN-PAGE) 分析。

生化/生理作用

正十二烷基β-D-D-麦芽糖苷(DDM)具有生物相容性和生物降解性。 作为电子转移的促进剂可降低 3,4-乙撑二氧噻吩(EDOT)的氧化电位。它还可以增加EDOT在水溶液中的溶解度。

包装

125 mL棕色螺旋盖宽口玻璃瓶 (850520P-25g)
20 mL透明玻璃螺旋盖小瓶(850520P-1g)
30 mL棕色广口螺旋盖玻璃瓶(850520P-5g)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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访问文档库

Anastasiia Gusach et al.
Nature communications, 10(1), 5573-5573 (2019-12-08)
Cysteinyl leukotriene G protein-coupled receptors CysLT1 and CysLT2 regulate pro-inflammatory responses associated with allergic disorders. While selective inhibition of CysLT1R has been used for treating asthma and associated diseases for over two decades, CysLT2R has recently started to emerge as
Electrochemical polymerization of 3, 4-ethylenedioxythiophene in aqueous solution containing N-dodecyl-beta-d-maltoside
Zhang S, et al.
European Polymer Journal, 42(1), 149-160 (2006)
Truc Do et al.
Nature microbiology, 5(2), 291-303 (2020-01-15)
Bacteria are protected by a polymer of peptidoglycan that serves as an exoskeleton1. In Staphylococcus aureus, the peptidoglycan assembly enzymes relocate during the cell cycle from the periphery, where they are active during growth, to the division site where they
Biallelic mutations in ATP5F1D, which encodes a subunit of ATP synthase, cause a metabolic disorder
Olahova M, et al.
American Journal of Human Genetics, 102(3), 494-504 (2018)
Xiaoxu Jiang et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(12), E698-E704 (2012-02-23)
LacY mutant Cys154 → Gly exhibits a periplasmic-closed crystal structure identical to the WT, but is periplasmic-open in the membrane. The mutant hardly catalyzes transport, but binds galactosides from either side of the membrane with the same affinity and is

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