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Merck
CN

850480C

Avanti

16:0-18:0 (6-7BR) PC

Avanti Research - A Croda Brand

别名:

1-hexadecanoyl-2-(6,7-dibromooctadecanoyl)-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C42H82NO8PBr2
化学文摘社编号:
分子量:
919.88
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

16:0-18:0 (6-7BR) PC, 1-palmitoyl-2-(6,7-dibromo)stearoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (850480C-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850480C

concentration

10 mg/mL (850480C-10mg)

lipid type

omega FAs
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

16:0-18:0 (6-7BR) PC (1-palmitoyl-2-(6,7-dibromo) stearoyl-sn-glycero-3-phosphocholine) may be used:
  • to prepare large unilamellar liposomes for parallax analysis
  • in phospholipid vesicle preparation for tryptophan (Trp) penetration depth experiments
  • to study the effect of bromination at different positions along the fatty acid chains

Biochem/physiol Actions

16:0-18:0 (6-7BR) PC (1-palmitoyl-2-(6,7-dibromo) stearoyl-sn-glycero-3-phosphocholine) serves as a shallow quencher.

General description

16:0-18:0 (6-7BR) PC (1-palmitoyl-2-(6,7-dibromo) stearoyl-sn-glycero-3-phosphocholine) is a brominated-PC lipid.

Packaging

5 mL Clear Glass Sealed Ampule (850480C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

法规信息

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分析证书(COA)

Lot/Batch Number

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Tim Rasmussen et al.
Journal of molecular biology, 431(17), 3339-3352 (2019-06-08)
All membrane proteins have dynamic and intimate relationships with the lipids of the bilayer that may determine their activity. Mechanosensitive channels sense tension through their interaction with the lipids of the membrane. We have proposed a mechanism for the bacterial
Johanna C Karst et al.
The Journal of biological chemistry, 287(12), 9200-9212 (2012-01-14)
The adenylate cyclase (CyaA) toxin, one of the virulence factors secreted by Bordetella pertussis, the pathogenic bacteria responsible for whooping cough, plays a critical role in the early stages of respiratory tract colonization by this bacterium. The CyaA toxin is
John M Harrington et al.
PloS one, 7(9), e44384-e44384 (2012-09-13)
The bloodstream developmental forms of pathogenic African trypanosomes are uniquely susceptible to killing by small hydrophobic peptides. Trypanocidal activity is conferred by peptide hydrophobicity and charge distribution and results from increased rigidity of the plasma membrane. Structural analysis of lipid-associated
Candace M Pfefferkorn et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2821-2828 (2015-08-25)
Apolipoproteins are essential human proteins for lipid metabolism. Together with phospholipids, they constitute lipoproteins, nm to μm sized particles responsible for transporting cholesterol and triglycerides throughout the body. To investigate specific protein-lipid interactions, we produced and characterized three single-Trp containing

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