描述
1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine
检测方案
>99% (TLC)
形式
powder
包装
pkg of 2 × 100 mg (850475P-200mg)
pkg of 1 × 25 mg (850475P-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
InChI
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI key
RRVPPYNAZJRZFR-VYOBOKEXSA-N
应用
18:0-16:0 PC(1-油酰基-2-棕榈酰基-sn-甘油-3-磷酸胆碱)已用于:
- 可用作超高效液相色谱(UPLC)分析中的脂质标准品
- 用作脂质体中的一种成分研究几种细胞系的细胞增殖
- 用作脂质体以进行交联实验(5)
生化/生理作用
磷脂酰胆碱(PC)可以通过充当表面活性剂在粘液中形成疏水表面,从而抑制细菌的渗透。
包装
5 mL透明玻璃密封安瓿(850475P-200mg)
5 mL透明玻璃密封安瓿(850475P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Analytical and bioanalytical chemistry, 411(4), 915-924 (2018-12-24)
Diacyl glycerophospholipids (GPs) belong to the most abundant lipid species in living organisms and consist of a glycerol backbone with fatty acyl groups in sn-1 and sn-2 and a polar head group in the sn-3 position. Regioisomeric mixed diacyl GPs
Nature communications, 7, 11726-11726 (2016-05-25)
Autophagy is responsible for the bulk degradation of cytosolic constituents and plays an essential role in the intestinal epithelium by controlling beneficial host-bacterial relationships. Atg5 and Atg7 are thought to be critical for autophagy. However, Atg5- or Atg7-deficient cells still
Nanomedicine : nanotechnology, biology, and medicine, 24, 102154-102154 (2020-01-27)
In vivo delivery of large RNA molecules has significant implications for novel gene therapy, biologics delivery, and vaccine applications. We have developed cationic nanolipoprotein particles (NLPs) to enhance the complexation and delivery of large self-amplifying mRNAs (replicons) in vivo. NLPs
Biochimica et biophysica acta, 1848(7), 1599-1608 (2015-04-29)
According to early experiments with natural extracts, phosphatidylcholines (PCs) are widely considered essentially non-toxic. In addition to these physiological mixed-chain PCs, many different synthetic diacyl-PCs are currently available, but they have never been systematically evaluated for any interference with cell
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