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描述
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 1 g (850457P-1g)
pkg of 2 × 100 mg (850457P-200mg)
pkg of 5 × 100 mg (850457P-500mg)
pkg of 1 × 25 mg (850457P-25mg)
制造商/商品名称
Avanti Polar Lipids
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI key
WTJKGGKOPKCXLL-VYOBOKEXSA-N
一般描述
POPC通常被作为一种模型脂质,用于生物物理实验。脂肪酸组分,即sn-1位的饱和链和sn-2位的不饱和链,可模拟哺乳动物的磷脂组分。由于Egg PC的主要成分是1-棕榈酰-2-油酰PC,因此,POPC是EPC的优良合成替代品。
应用
16:0-18:1 PC用于制备脂质体,包裹胞壁酰三肽。也用于制备膜支架蛋白1纳米光盘。16:0-18:1 PC可用于合成盘状重构的高密度脂蛋白。
生化/生理作用
1-棕榈酰-2-油酰-甘油-3-磷酸胆碱(POPC)或16:0-18:1 PC作为肺表面活性剂发挥重要作用,降低表面张力。POPC模拟天然细胞膜,可用于不饱和脂质的氧化研究。它与臭氧相互作用,使油酰链C-C键氧化分解。
包装
5 mL透明玻璃密封安瓿瓶(850457P-200mg)
5 mL透明玻璃密封安瓿瓶(850457P-25mg)
5 mL透明玻璃密封安瓿瓶(850457P-500mg)
60 mL琥珀色宽口螺帽玻璃瓶(850457P-1g)
通常也和此产品一起购买
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Oxidative degradation of the monolayer of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) in low-level ozone
The Journal of Physical Chemistry B, 119(44), 14188-14199 (2015)
Modified apolipoprotein (apo) AI by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state
Molecules and Cells, 31(5), 461-470 (2011)
Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Bio-protocol, 7(12) (2017)
ACS nano, 12(5), 4478-4485 (2018-04-17)
Giant unilamellar vesicles (GUVs) provide a direct connection between the nano- and the microregime. On the one hand, these vesicles represent biomimetic compartments with linear dimensions of many micrometers. On the other hand, the vesicle walls are provided by single
Biochemistry, 57(50), 6897-6905 (2018-11-21)
The plasma membrane of the cell is a complex, tightly regulated, heterogeneous environment shaped by proteins, lipids, and small molecules. Ca2+ ions are important cellular messengers, spatially separated from anionic lipids. After cell injury, disease, or apoptotic events, anionic lipids
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