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经验公式(希尔记法):
C38H76NO8P
化学文摘社编号:
分子量:
705.99
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
14:0-16:0 PC, 1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
InChI
1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1
InChI key
RFVFQQWKPSOBED-PSXMRANNSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850445P-25mg)
pkg of 1 × 500 mg (850445P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850445P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
- in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
- as a negative control in stimulation studies to study its effect on insect immune deficiency (IMD) pathway
- in generating Wnt3a liposomes
Biochem/physiol Actions
Phosphatidylcholines (PCs) participates in reducing the level of blood lipid and cholesterol.
General description
Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of animal. PCs consist of saturated and unsaturated fatty acids in the sn-1 and sn-2 position respectively.
Packaging
20 mL Clear Glass Screw Cap Vial (850445P-500mg)
5 mL Amber Glass Screw Cap Vial (850445P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Essentials of Medical Biochemistry, 299-320 (2015)
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Nathan T Morrell et al.
PloS one, 3(8), e2930-e2930 (2008-08-14)
Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.
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