检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 25 mg (850445P-25mg)
pkg of 1 × 500 mg (850445P-500mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 850445P
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
InChI
1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1
InChI key
RFVFQQWKPSOBED-PSXMRANNSA-N
一般描述
Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of animal. PCs consist of saturated and unsaturated fatty acids in the sn-1 and sn-2 position respectively.
应用
14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
- in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
- as a negative control in stimulation studies to study its effect on insect immune deficiency (IMD) pathway
- in generating Wnt3a liposomes
生化/生理作用
Phosphatidylcholines (PCs) participates in reducing the level of blood lipid and cholesterol.
包装
20 mL Clear Glass Screw Cap Vial (850445P-500mg)
5 mL Amber Glass Screw Cap Vial (850445P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Essentials of Medical Biochemistry, 299-320 (2015)
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Dana K Shaw et al.
Nature communications, 8, 14401-14401 (2017-02-15)
The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids
Nathan T Morrell et al.
PloS one, 3(8), e2930-e2930 (2008-08-14)
Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and
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