所有图片(2)
别名:
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; MPPC; PC(14:0/16:0)
经验公式（希尔记法）:
C38H76NO8P
推荐产品
检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 2.5 mL (850445C-25mg)
pkg of 1 × 20 mL (850445C-500mg)
制造商/商品名称
Avanti Polar Lipids 850445C
浓度
10 mg/mL (850445C-25mg)
25 mg/mL (850445C-500mg)
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
InChI
1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1
InChI key
RFVFQQWKPSOBED-PSXMRANNSA-N
一般描述
Phosphatidylcholine (PC) is dietary source of choline. 14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) is a water-soluble lysolipid. 14:0-16:0 PC is a symmetrical phosphatidylcholine.
应用
14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) has been used to generate Wnt3a liposomes. It has also been used as a calibration standard for lipidomic analysis by liquid chromatography–tandem mass spectrometry (LC-MS). It may be used in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC).
生化/生理作用
Phosphatidylcholine (PC) is involved in the fusion and transport of membranes. It is known to play a vital role in endocytosis and the catalytic activity of enzymes.
包装
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850445C-500mg)
5 mL Clear Glass Sealed Ampule (850445C-25mg)
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
靶器官
Liver,Kidney, Respiratory system
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
新产品
Jeffrey K Mills et al.
Biochimica et biophysica acta, 1716(2), 77-96 (2005-10-12)
The enhanced permeability of lipid bilayer membranes at their gel-to-liquid phase transition has been explained using a "bilayer lipid heterogeneity" model, postulating leaky interfacial regions between still solid and melting liquid phases. The addition of lysolipid to dipalmitoylphosphatidylcholine bilayers dramatically
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Ségolène Hescot et al.
Oncotarget, 8(66), 109924-109940 (2018-01-05)
Mitotane (o,p'DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches as well as imaging analyses
Dana K Shaw et al.
Nature communications, 8, 14401-14401 (2017-02-15)
The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids
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