所有图片(2)
别名:
1,2-di-(15Z-tetracosenoyl)-sn-glycero-3-phosphocholine; PC(24:1(15Z)/24:1(15Z)); 110930
经验公式（希尔记法）:
C56H108NO8P
推荐产品
检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 25 mg (850399P-25mg)
制造商/商品名称
Avanti Polar Lipids 850399P
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)=O
InChI
1S/C56H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-48-55(58)62-52-54(53-64-66(60,61)63-51-50-57(3,4)5)65-56(59)49-47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,54H,6-19,24-53H2,1-5H3/b22-20-,23-21-/t54-/m1/s1
InChI key
REWNAIYQZZOESC-CGKZWXATSA-N
一般描述
24:1 (Cis) PC (1,2-dinervonoyl-sn-glycero-3-phosphocholine) has two 24 carbon fatty acid chains, each having one cis double bond at the 15th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
应用
24:1 (Cis) PC (1,2-dinervonoyl-sn-glycero-3-phosphocholine) may be used in planar bilayer lipid membranes (BLMs) to study the effect of lipid chain length on single-channel properties of C-terminal colicin peptide (P178). It may also be used in planar bilayers to explore the single channel activities of BKCa (hSlo α-subunit) channels.
生化/生理作用
Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation.
包装
5 mL Clear Glass Sealed Ampule (850399P-25mg)
Chunbo Yuan et al.
The Journal of biological chemistry, 282(10), 7276-7286 (2007-01-09)
Transmembrane segments of ion channels tend to match the hydrophobic thickness of lipid bilayers to minimize mismatch energy and to maintain their proper organization and function. To probe how ion channels respond to mismatch with lipid bilayers of different thicknesses
Luciana Paoletti et al.
IUBMB life, 63(9), 714-720 (2011-08-06)
Neuronal differentiation is characterized by neuritogenesis and neurite outgrowth, processes, which are critically dependent on membrane biosynthesis, and therefore, on the expression and regulation of enzymes involved in phospholipid biosynthesis. During the last decade a great effort was made to
Alexander A Sobko et al.
The Journal of biological chemistry, 281(20), 14408-14416 (2006-03-25)
Colicin E1 belongs to a group of bacteriocins whose cytotoxicity toward Escherichia coli is exerted through formation of ion channels that depolarize the cytoplasmic membrane. The lipid dependence of colicin single-channel conductance demonstrated intimate involvement of lipid in the structure
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