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Merck
CN

850396P

Avanti

20:1 (Cis) PC

1,2-dieicosenoyl-sn-glycero-3-phosphocholine, powder

别名:

1,2-di-(11Z-eicosenoyl)-sn-glycero-3-phosphocholine; PC(20:1(11Z)/20:1(11Z))

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About This Item

经验公式(希尔记法):
C48H92NO8P
CAS号:
分子量:
842.22
UNSPSC代码:
51191904
NACRES:
NA.25

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 25 mg (850396P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 850396P

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCC/C=C\CCCCCCCC)=O)=O

InChI

1S/C48H92NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,46H,6-19,24-45H2,1-5H3/b22-20-,23-21-/t46-/m1/s1

InChI key

AEUCYCQYAUFAKH-DITNKEBASA-N

一般描述

20:1 (Cis) PC (1,2-dieicosenoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It has two 20 carbon fatty acid chains, each having one cis double bond at the 11th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

应用

20:1 (Cis) PC (1,2-dieicosenoyl-sn-glycero-3-phosphocholine) may be used:
  • as an internal standard for mass spectrometric analysis
  • to prepare large multilamellar vesicles for proteoliposome generation
  • to study the effects of the lipid chain length on 6-bromoacetyl-2-dimethylaminonaphthalene (BADAN) fluorescence parameters

生化/生理作用

Phosphatidylcholine (PC) is known to participate in the fusion and transport of membranes.

包装

5 mL Clear Glass Sealed Ampule (850396P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rob B M Koehorst et al.
Biophysical journal, 94(10), 3945-3955 (2008-02-01)
The work presented here describes a new and simple method based on site-directed fluorescence labeling using the BADAN label that permits the examination of protein-lipid interactions in great detail. We applied this technique to a membrane-embedded, mainly alpha-helical reference protein
Metabolic Heavy Isotope Labeling to Study Glycerophospholipid Homeostasis of Cultured Cells
Hanninen S, et al.
Bio-protocol, 7(9) (2017)
Larisa E Cybulski et al.
Current biology : CB, 20(17), 1539-1544 (2010-08-14)
Thermosensors are ubiquitous integral membrane proteins found in all kinds of life. They are involved in many physiological roles, including membrane remodeling, chemotaxis, touch, and pain [1-3], but, the mechanism by which their transmembrane (TM) domains transmit temperature signals is
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.

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