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Merck
CN

850356P

Avanti

4ME 16:0 PC

Avanti Research - A Croda Brand

别名:

1,2-二-(3,7,11,15- tetramethylhexadecanoyl)-sn-甘油-3-磷酸胆碱;PC(16:0(3ME,7ME,11me,15me)/ 16:0(3ME,7ME,11me,15me))

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About This Item

经验公式(希尔记法):
C48H96NO8P
分子量:
846.25
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

描述

1,2-diphytanoyl-sn-glycero-3-phosphocholine

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 200 mg ((850356P-200MG))
pkg of 1 × 25 mg ((850356P-25MG))
pkg of 1 × 500 mg ((850356P-500MG))

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O

InChI

1S/C48H96NO8P/c1-38(2)20-14-22-40(5)24-16-26-42(7)28-18-30-44(9)34-47(50)54-36-46(37-56-58(52,53)55-33-32-49(11,12)13)57-48(51)35-45(10)31-19-29-43(8)27-17-25-41(6)23-15-21-39(3)4/h38-46H,14-37H2,1-13H3/t40?,41?,42?,43?,44?,45?,46-/m1/s1

InChI key

UKDDQGWMHWQMBI-SOFRWFQSSA-N

一般描述

含有二羟基脂肪酸链的脂质已用于产生稳定的平面脂质膜(参见参考文献)。植烷酰磷脂酰胆碱在 -120℃ 至 + 120℃ 的液晶相转变中没有表现出可检测的凝胶。Avanti 提供的磷脂酰胆碱产品列表旨在提供具有多种物理性质的化合物。可用产品包括短链(C3-C8 是水溶性和吸湿性的),饱和、多不饱和和混合酸 PC′s。所有产品均通过高效液相色谱纯化,并采取特殊预防措施,以保护产品免受氧化和水解。

应用

4ME 16:0 PC用于:
  • 氯离子通道的电生理研究
  • 生成液滴-水凝胶双层(DHB),用于蛋白重建研究
  • 生成脂质双层,用于单通道和离子选择性测量研究

生化/生理作用

1,2-二植烷酰基-sn-甘油-3-磷酸胆碱(4ME 16:0 Pc)或 DPhPC 具有胆碱头部基团,有利于形成膜脂质双层。 显示出对离子和水的低渗透性。DPhPC 是主要用于电生理测量和离子电导性研究的脂质。

包装

20 mL 透明玻璃螺旋盖小瓶(850356P-200mg)
30 mL 带螺旋盖的琥珀宽口瓶(850356P-500mg)
5 mL 透明玻璃密封安瓿(850356P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Physical properties of bilayer membranes formed from a synthetic saturated phospholipid in n-decane.
W R Redwood et al.
Biochimica et biophysica acta, 233(1), 1-6 (1971-03-09)
Tim Diederichs et al.
Nature communications, 10(1), 5018-5018 (2019-11-07)
Nanopores are key in portable sequencing and research given their ability to transport elongated DNA or small bioactive molecules through narrow transmembrane channels. Transport of folded proteins could lead to similar scientific and technological benefits. Yet this has not been
Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae
Pathania M, et al.
Structure, 26(5), 708-721 (2018)
Chan Cao et al.
Nature communications, 10(1), 4918-4918 (2019-10-31)
Nanopore sensing is a powerful single-molecule approach for the detection of biomolecules. Recent studies have demonstrated that aerolysin is a promising candidate to improve the accuracy of DNA sequencing and to develop novel single-molecule proteomic strategies. However, the structure-function relationship
H Lindsey et al.
Biochimica et biophysica acta, 555(1), 147-167 (1979-07-19)
We report here on a series of studies aimed at characterization of the structural and dynamical properties of the synthetic lipid diphytanoyl phosphatidylcholine, in multilamellar dispersions and vesicle suspensions. The lipid exhibits no detectable gel to liquid crystalline phase transition

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