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Merck
CN

850350C

Avanti

15:0 PC

Avanti Research™ - A Croda Brand

别名:

PC(15:0/15:0)

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关于此项目

经验公式（希尔记法）:
C38H76NO8P
化学文摘社编号:
3355-27-9
分子量:
705.99
MDL number:
MFCD00063522
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

15:0 PC, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[P](=O)(OCC[N+](C)(C)C)(OCC(OC(=O)CCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)O

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-37(40)44-34-36(35-46-48(42,43)45-33-32-39(3,4)5)47-38(41)31-29-27-25-23-21-19-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/p+1

InChI key

LJARBVLDSOWRJT-UHFFFAOYSA-O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850350C-25mg)
pkg of 2 × 4 mL (850350C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850350C

concentration

10 mg/mL (850350C-25mg)
25 mg/mL (850350C-200mg)

shipped in

dry ice

storage temp.

−20°C

Application

15:0 PC (1,2-dipentadecanoyl-sn-glycero-3-phosphocholine) may be used:
  • as a component in fluidizing lipid bilayers to study the role of membrane fluidity in mediating membrane sensitivity to small hydrophobic peptides or haptoglobin-related protein (SHP-1)
  • to prepare giant unilamellar lipid vesicles (GUVs)
  • to construct supported phospholipid bilayers to study the gel-fluid phase transition behavior using in situ, temperature-dependent atomic force microscopy

Biochem/physiol Actions

Phosphatidylcholine (PC) is capable of preventing the penetrance of bacteria by acting as a surfactant. This phospholipid is capable of forming a strong bilayer.

General description

Phosphatidylcholine (PC) carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Packaging

5 mL Clear Glass Sealed Ampule (850350C-200mg)
5 mL Clear Glass Sealed Ampule (850350C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

法规信息

易制毒化学品（2类）
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Z Vivian Feng et al.
Biophysical journal, 88(3), 2154-2164 (2004-12-15)
We utilize in situ, temperature-dependent atomic force microscopy to examine the gel-fluid phase transition behavior in supported phospholipid bilayers constructed from 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The primary gel-fluid phase transition at T(m) occurs through development of anisotropic cracks in the
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Thomas Andersen et al.
Soft matter, 10(24), 4268-4274 (2014-05-02)
We reveal that the gel to fluid phase transition causes spherical membrane vesicles to release a finite number of molecules in several consecutive and localized events. By locally melting Giant Unilamellar lipid Vesicles (GUVs), using an optically trapped gold nanoparticle
Yasuhiro Horibata et al.
Scientific reports, 10(1), 2845-2845 (2020-02-20)
StarD7 is a phosphatidylcholine (PC)-specific lipid transfer protein essential for the maintenance of mitochondrial PC composition, morphogenesis, and respiration. Here, we studied the role of StarD7 in skeletal myoblast differentiation using mouse myoblast C2C12 cells and human primary myoblasts. Immunofluorescence
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