检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 2.5 mL (850346C-25mg)
pkg of 2 × 4 mL (850346C-200mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 850346C
浓度
10 mg/mL (850346C-25mg)
25 mg/mL (850346C-200mg)
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
一般描述
Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
应用
14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.
生化/生理作用
Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
包装
5 mL Clear Glass Sealed Ampule (850346C-200mg)
5 mL Clear Glass Sealed Ampule (850346C-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
靶器官
Liver,Kidney, Respiratory system
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
易制毒化学品（2类）
危险化学品
The Membranes of Cells (2016)
Jiao Cao et al.
Nature communications, 10(1), 5668-5668 (2019-12-13)
Biological nanopores are capable of resolving small analytes down to a monoatomic ion. In this research, tetrachloroaurate(III), a polyatomic ion, is discovered to bind to the methionine residue (M113) of a wild-type α-hemolysin by reversible Au(III)-thioether coordination. However, the cylindrical
Interference of phosphatidylcholines with in vitro cell proliferation?no flock without black sheep
Werlein A, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(7), 1599-1608 (2015)
Bilayer thickness and curvature influence binding and insertion of a pHLIP peptide
Karabadzhak AG, et al.
Biophysical Journal, 114(9), 2107-2115 (2018)
Integrative Medicine - E-Book (2017)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门