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Merck
CN
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安全信息

850335C

Avanti

12:0 PC (DLPC)

1,2-dilauroyl-sn-glycero-3-phosphocholine, chloroform

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别名:
1,2-didodecanoyl-sn-glycero-3-phosphocholine; DLPC; PC(12:0/12:0)
经验公式（希尔记法）:
C32H64NO8P
CAS号:
18194-25-7
分子量:
621.83
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (850335C-25mg)
pkg of 1 × 20 mL (850335C-500mg)
pkg of 2 × 4 mL (850335C-200mg)

制造商/商品名称

Avanti Polar Lipids 850335C

浓度

10 mg/mL (850335C-25mg)
25 mg/mL (850335C-200mg)
25 mg/mL (850335C-500mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

InChI

1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m0/s1

InChI key

IJFVSSZAOYLHEE-PMERELPUSA-N

相关类别

一般描述

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
The mucosal layer of the colon has phosphatidylcholine (PC). PCs carry fatty acids in the sn-1 and sn-2 positions, that are covalently attached to a glycerol through ester bonds.

应用

12:0 PC (DLPC/1,2-dilauroyl-sn-glycero-3-phosphocholine) may be used as a standard to quantify phosphatidylcholine. It has also been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions.

生化/生理作用

Phosphatidylcholine (PC) has the ability to block the penetrance of bacteria by acting as a surfactant.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850335C-500mg)
5 mL Clear Glass Sealed Ampule (850335C-200mg)
5 mL Clear Glass Sealed Ampule (850335C-25mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

易制毒化学品（2类）
危险化学品

分析证书(COA)

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Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol, 6, 1849e-1849e null
Comprehensive untargeted lipidomic analysis using core
Narvaaez R, et al.
Journal of Chromatography A, 1440, 123-134 null
Nhiem Tran et al.
The journal of physical chemistry letters, 9(12), 3397-3402 (2018-05-29)
The transition between the lyotropic liquid crystalline lamellar and the bicontinuous cubic mesophase drives multiple fundamental cellular processes involving changes in cell membrane topology, including endocytosis and membrane budding. While several theoretical models have been proposed to explain this dynamic
John P Kowalski et al.
Chemical research in toxicology, 32(12), 2488-2498 (2019-12-05)
Cytochrome P450 4B1 (CYP4B1) has been explored as a candidate enzyme in suicide gene systems for its ability to bioactivate the natural product 4-ipomeanol (IPO) to a reactive species that causes cytotoxicity. However, metabolic limitations of IPO necessitate discovery of
Inflammatory Bowel Disease
Parian AM, et al.
Integrative Medicine, 501-516 null
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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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