检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 100 mg (850311P-100mg)
pkg of 1 × 200 mg (850311P-200mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 850311P
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[H]C(C[N+](C)(CCOP([O-])(O)=O)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
一般描述
反向磷酸胆碱脂质是常见磷脂的再混合物，其头基相对于磷酸胆碱（PC）脂质具有相反的电荷方向。iPC脂质头基具有与双层界面相邻的季胺和延伸到水相中的磷酸盐。因此，iPC脂质提供了一个独特的机会来研究双层表面电荷反转的生物物理和生物活性相关分支。
应用
DOCP适用于制备
- 用于人C反应蛋白结合研究的支持性磷脂单层
- 大单层囊泡（LUVs）
- 用于人星形胶质细胞摄取研究的脂质体
包装
20 mL透明玻璃螺旋盖小瓶（850311P-200mg）
5 mL棕色玻璃螺旋盖小瓶（850311P-100mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Specific binding of human C-reactive protein towards supported monolayers of binary and engineered phospholipids
Goda T and Miyahara Y
Colloids and Surfaces. B, Biointerfaces, 161, 662-669 (2018)
Sulfocerebrosides upregulate liposome uptake in human astrocytes without inducing a proinflammatory response
Suesca , et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 83(7), 627-635 (2013)
Inorganic cadmium affects the fluidity and size of phospholipid based liposomes
Kerek EM and Prenner EJ
Biochimica et Biophysica Acta - Biomembranes, 1858(12), 3169-3181 (2016)
Yibo Liu et al.
Langmuir : the ACS journal of surfaces and colloids, 34(32), 9337-9348 (2018-03-13)
Phospholipids are a major component of the cell membrane. In most natural phospholipids, the phosphate acts as a bridge, connecting the other portion of the polar headgroup with the hydrophobic tails. Such bridging phosphate is chemically quite inert. Synthetic lipids
Emily K Perttu et al.
Journal of the American Chemical Society, 134(10), 4485-4488 (2012-03-01)
Zwitterionic inverse-phosphocholine (iPC) lipids contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Neutral iPC
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