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Merck
CN

850311C

Avanti

DOCP

Avanti Research - A Croda Brand 850311C

别名:

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate

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About This Item

经验公式(希尔记法):
C43H82NO8P
分子量:
772.09
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (850311C-25mg)
pkg of 2 × 4 mL (850311C-200mg)

制造商/商品名称

Avanti Research - A Croda Brand 850311C

浓度

10 mg/mL (850311C-25mg)
25 mg/mL (850311C-200mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

一般描述

DOCP is a zwitterionic /negatively charged lipid. It possess an inverse headgroup This synthetic molecule has stronger affinity than 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS).
Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.

应用

DOCP is suitable for use in the preparation of large unilamellar vesicles (LUVs) and in the preparation of liposomes.

包装

5 mL Clear Glass Sealed Ampule (850311C-200mg)
5 mL Clear Glass Sealed Ampule (850311C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

危险化学品
易制毒化学品(2类)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Partition of Positively and Negatively Charged Tryptophan Ions in Membranes with Inverted Phospholipid Heads: Simulations and Experiments
Cardenas AE, et al.
The Journal of Physical Chemistry B (2019)
A Stable Lipid/TiO2 Interface with headgroup-inversed phosphocholine and a comparison with SiO2
Wang F and Liu J
Journal of the American Chemical Society, 137(36), 11736-11742 (2015)
Inorganic cadmium affects the fluidity and size of phospholipid based liposomes
Kerek EM and Prenner EJ
Biochimica et Biophysica Acta - Biomembranes, 1858(12), 3169-3181 (2016)
Charge and Coordination Directed Liposome Fusion onto SiO2 and TiO2 Nanoparticles
Wang X, et al.
Langmuir, 35(5), 1672-1681 (2018)
Emily K Perttu et al.
Journal of the American Chemical Society, 134(10), 4485-4488 (2012-03-01)
Zwitterionic inverse-phosphocholine (iPC) lipids contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Neutral iPC

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