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Merck
CN

850303C

Avanti

04:0 PC

1,2-dibutyryl-sn-glycero-3-phosphocholine, chloroform

别名:

PC(4:0/4:0)

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About This Item

经验公式(希尔记法):
C16H32NO8P
CAS号:
分子量:
397.40
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (850303C-25mg)
pkg of 1 × 20 mL (850303C-500mg)

制造商/商品名称

Avanti Research - A Croda Brand 850303C

浓度

10 mg/mL (850303C-25mg)
25 mg/mL (850303C-500mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

InChI

1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1

InChI key

QIJYAMAPPUXBSC-CQSZACIVSA-N

一般描述

Phosphatidylcholine (PC) is dietary source of choline. 04:0 PC (1,2-dibutyryl-sn-glycero-3-phosphocholine) is a short chain fatty acyl residue.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

应用

04:0 PC (1,2-dibutyryl-sn-glycero-3-phosphocholine) may be used:
  • to study its influence on the formation of lipid hydroperoxides and headspace hexanal in stripped soybean oil (SSO)
  • to study its impact on the antioxidant activity of α-tocopherol
  • as a phospholipid substrate to study the substrate specificity of the purified glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP)
  • as a substrate to study the activities of soluble and immobilized phospholipase 2 from snake venom

生化/生理作用

Phosphatidylcholine (PC) intake through diet can enhance the learning and memory ability in rats.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850303C-500mg)
5 mL Clear Glass Sealed Ampule (850303C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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Bingcan Chen et al.
Food & function, 2(6), 302-309 (2011-07-23)
Phospholipids self-assemble in bulk oils to form structures such as reverse micelles that can alter the microenvironment where chemical degradation reactions occur, such as lipid oxidation. In this study, we examined the influence of phospholipid reverse micelles on the activity
Z Shen et al.
Journal of lipid research, 36(5), 1147-1151 (1995-05-01)
A new method for the immobilization of phospholipase A2 (PLA2) has been developed to enhance the activity retention of immobilized PLA2. When PLA2 from the venom of Agkistrodon piscivorus piscivorus was pretreated with 4-nitro-3-octanoyl-oxybenzoic acid to acylate epsilon-amino groups of
A Plückthun et al.
Biochemistry, 21(8), 1750-1756 (1982-04-13)
Phospholipase A2 from cobra venom (Naja naja naja), which acts poorly on phosphatidylethanolamine (PE) in mixed micelles, is activated toward PE by the monomeric phospholipid dibutyrylphosphatidylcholine (dibutyryl-PC) which is an, even poorer substrate. Phosphorus-31 nuclear magnetic resonance spectroscopy was employed
W R Bishop et al.
Cell, 42(1), 51-60 (1985-08-01)
Phospholipids are synthesized and concomitantly inserted on the cytoplasmic surface of the endoplasmic reticulum. Assembly of the phospholipid bilayer requires translocation to the lumenal monolayer. The hypothesis that rat liver microsomes contain a protein transporter, or "flippase," for phosphatidylcholine was
F Berr et al.
The Journal of biological chemistry, 268(6), 3976-3979 (1993-02-25)
In the present study we used the water-soluble short chain phosphatidylcholine analogue L-alpha-dibutyryl-glycero-3-phosphatidylcholine (diC4PC) to investigate the mechanism involved in the canalicular secretion of phospholipids in rat liver. Uptake of 14C-labeled di-C4PC was studied in isolated microsomes as well as

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