检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 100 μg (with stopper and crimp cap (850115P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850115P-500ug))
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](OP(O)([O-])=O)[C@@H]1OP([O-])(O)=O)OP(O)([O-])=O.[NH4+].[NH4+].[NH4+]
应用
IP3（1，4，5）已被用作补充剂，以在激酶-Glo发光激酶测定中处理纯化的肌醇1，4，5-三磷酸3-激酶A（IP3K-A）重组蛋白。
生化/生理作用
肌醇1，4，5-三磷酸（IP3）充当第二信使。IP3能够从内质网释放钙。IP3有助于调节肌醇1，4，5-三磷酸（IRBIT）释放的IP3R结合蛋白与肌醇1，4，5-三磷酸受体（IP3R）之间的交互效应。
包装
带塞子和压接盖的2 mL棕色血清瓶（850115P-100ug）
带塞子和压接盖的2 mL棕色血清瓶（850115P-500ug）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Hideaki Ando et al.
The Journal of biological chemistry, 278(12), 10602-10612 (2003-01-15)
The inositol 1,4,5-trisphosphate (IP(3)) receptors (IP(3)Rs) are IP(3)-gated Ca(2+) channels on intracellular Ca(2+) stores. Herein, we report a novel protein, termed IRBIT (IP(3)R binding protein released with inositol 1,4,5-trisphosphate), which interacts with type 1 IP(3)R (IP(3)R1) and was released upon
Dongmin Lee et al.
Protein expression and purification, 97, 72-80 (2014-03-01)
Inositol 1,4,5-trisphosphate 3-kinase A (IP3K-A, alternative name: ITPKA) is a neuron-specific enzyme that converts 1,4,5-trisphosphate (IP3) into inositol 1,3,4,5-tetrakisphosphate (IP4) through its kinase domain. In addition, transient overexpression of IP3K-A induces morphological changes in dendritic spines of excitatory synapses in
Spinocerebellar ataxia type 14
Handbook of Clinical Neurophysiology, 103, 555-559 null
Jack D Thatcher
Science signaling, 3(119), tr3-tr3 (2010-04-29)
This resource provides and describes two animated lessons that illustrate inositol 1,4,5-trisphosphate signal transduction pathways. They are designed for any collegiate-level course that presents the basic steps of the prototypical pathway. Courses that might employ these animations include Introductory Biology
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