检测方案
>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
形式
powder
包装
pkg of 1 × 10 mg (850091P-10mg)
pkg of 1 × 5 mg (850091P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 850091P
脂质类型
phosphoglycerides
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
一般描述
Lysophosphotidylinositol (LPI) is a bioactive lipid obtained from the phospholipase A (PLA) family of lipases.
应用
Liver Lyso PI has been used to enhance the binding efficiency of ovalbumin peptide to class II major histocompatibility molecules.
生化/生理作用
Lysophosphotidylinositol (LPI) is involved in metabolism and glucose homeostasis. It also affects cellular growth, differentiation and motility of various cells, such as nerve cells, endothelial cells and cancer cells. LPI is an endogenous ligand for G-protein coupled receptor, GPR55.
包装
5 mL Amber Glass Screw Cap Vial (850091P-10mg)
5 mL Amber Glass Screw Cap Vial (850091P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
The lysophosphatidylinositol receptor GPR55 modulates pain perception in the periaqueductal gray
Deliu E, et al.
Molecular Pharmacology, 88(2), 265-272 (2015)
Lysophosphatidylinositol signalling and metabolic diseases
Arifin S A and Falasca M
Metabolites, 6(1), 6-6 (2016)
Phospholipids enhance the binding of peptides to class II major histocompatibility molecules
Roof R W, et al.
Proceedings of the National Academy of Sciences of the USA, 87(5), 1735-1739 (1990)
Ieva Ailte et al.
Scientific reports, 6, 30336-30336 (2016-07-28)
Shiga toxin (Stx), an AB5 toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells
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