推荐产品
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mL (841199C-10mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 841199C
浓度
10 mg/mL (841199C-10mg)
运输
dry ice
储存温度
−20°C
SMILES字符串
O=P([O-])(OC[C@]([H])(OC(CCCCCCCC1C(C1)CCCCCCC)=O)COC(CCCCCCCCCCCCCC)=O)OCC([H])(O)COP([O-])(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C/CCCCCCCC)=O)=O.[Na+].[Na+]
一般描述
Cardiolipin is a vital phospholipid of mitochondria. E.coli membrane is made of 5-10% of cardiolipin. Cardiolipin is a non-bilayer anionic phospholipid, that has four acyl chains and small headgroup.
生化/生理作用
Cardiolipin is implicated in the dynamic organization of membranes and in cell division. It is critical in proton uptake pathway.
包装
5 mL Clear Glass Sealed Ampule (841199C-10mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
新产品
Cardiolipin synthases of Escherichia coli have phospholipid class specific phospholipase D activity dependent on endogenous and foreign phospholipids
Jeucken A, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1863(10), 1345-1353 (2018)
Functional role of cardiolipin in mitochondrial bioenergetics
Paradies G, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1837(4), 408-417 (2014)
Targeting bacterial cardiolipin enriched microdomains: an antimicrobial strategy used by amphiphilic aminoglycoside antibiotics
El Khoury M, et al.
Scientific reports, 7(1), 10697-10697 (2017)
Javier Hoyo et al.
General physiology and biophysics, 39(2), 195-202 (2020-04-25)
The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers - the outer and the
Mikhail Bogdanov et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(34), 15057-15062 (2010-08-11)
Phosphatidylcholine (PC) has been widely used in place of naturally occurring phosphatidylethanolamine (PE) in reconstitution of bacterial membrane proteins. However, PC does not support native structure or function for several reconstituted transport proteins. Lactose permease (LacY) of Escherichia coli, when
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