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检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 10 mg (841188P-10mg)
pkg of 1 × 25 mg (841188P-25mg)
制造商/商品名称
Avanti Polar Lipids 841188P
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCC(C1)C1CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
一般描述
磷脂酰甘油（PG）是在大肠埃希菌内膜中发现的膜脂质。
应用
大肠埃希菌PG或L-α-磷脂酰甘油（大肠埃希菌）（钠盐）可用于：
- 作为脂质抗原以触发人类T细胞反应
- 作为质谱法（MS）中与磷脂酰甘油（PG）结合的哺乳动物细胞进入（MCE）蛋白的标准品
- 用于细菌模型膜中，以评估脂质-脂质各种相互作用，并有可能作为新型验证的模型
包装
5 mL透明玻璃密封安瓿（841188P-10mg）
5 mL透明玻璃密封安瓿（841188P-25mg）
Adam Shahine et al.
Science immunology, 2(16) (2017-10-22)
Human T cell autoreactivity toward lipid antigens presented by CD1 proteins can manifest in numerous diseases, including psoriasis, contact hypersensitivities, and allergies. However, the molecular mechanisms for regulating T cell autoreactivity toward lipid antigens remain unclear. We determined the basis
Damian C Ekiert et al.
Cell, 169(2), 273-285 (2017-04-08)
How phospholipids are trafficked between the bacterial inner and outer membranes through the hydrophilic space of the periplasm is not known. We report that members of the mammalian cell entry (MCE) protein family form hexameric assemblies with a central channel
Mikhail Bogdanov et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(34), 15057-15062 (2010-08-11)
Phosphatidylcholine (PC) has been widely used in place of naturally occurring phosphatidylethanolamine (PE) in reconstitution of bacterial membrane proteins. However, PC does not support native structure or function for several reconstituted transport proteins. Lactose permease (LacY) of Escherichia coli, when
Javier Hoyo et al.
General physiology and biophysics, 39(2), 195-202 (2020-04-25)
The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers - the outer and the
Ildiko Van Rhijn et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(2), 380-385 (2015-12-02)
In contrast with the common detection of T cells that recognize MHC, CD1a, CD1c, or CD1d proteins, CD1b autoreactive T cells have been difficult to isolate in humans. Here we report the development of polyvalent complexes of CD1b proteins and
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