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Merck
CN

840885P

Avanti

18:2 PA

1,2-dilinoleoyl-sn-glycero-3-phosphate (sodium salt), powder

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别名:
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate (sodium salt); PA(18:2(9Z,12Z)/18:2(9Z,12Z))
经验公式(希尔记法):
C39H68O8PNa
分子量:
718.92
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 25 mg (840885P-25mg)

制造商/商品名称

Avanti Polar Lipids 840885P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O.[Na+]

InChI

1S/C39H69O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h11-14,17-20,37H,3-10,15-16,21-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/b13-11-,14-12-,19-17-,20-18-;/t37-;/m1./s1

InChI key

UMYNPOZOTCNQKB-DKSSBCNHSA-M

一般描述

Phosphatidic acid (PA) is a precursor of lysophosphatidic acid (LPA) and is present in leafy vegetables.

应用

18:2 PA or 1,2-dilinoleoyl-sn-glycero-3-phosphate (sodium salt) might be used in saposin-derived lipid nanoparticle (SapNP) formation and in vacuolar mimic lipid (VML) proteoliposomes used for content-mixing assays.

包装

5 mL Clear Glass Sealed Ampule (840885P-25mg)

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Ali Flayhan et al.
Structure (London, England : 1993), 26(2), 345-355 (2018-02-08)
Saposin-derived lipid nanoparticles (SapNPs) are a new alternative tool for membrane protein reconstitution. Here we demonstrate the potential and advantages of SapNPs. We show that SapA has the lowest lipid specificity for SapNP formation. These nanoparticles are modular and offer
Hongki Song et al.
eLife, 9 (2020-01-22)
Yeast vacuole fusion requires R-SNARE, Q-SNAREs, and HOPS. A HOPS SM-family subunit binds the R- and Qa-SNAREs. We now report that HOPS binds each of the four SNAREs. HOPS catalyzes fusion when the Q-SNAREs are not pre-assembled, ushering them into
Mohamad Navab et al.
Journal of lipid research, 54(12), 3403-3418 (2013-10-03)
We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR⁻/⁻) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but

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