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Merck
CN

840875P

Avanti

18:1 PA

Avanti Research - A Croda Brand

别名:

1,2-二-(9Z-十八烯酰)--甘油-3-磷酸(钠盐);多巴;PA (18:1 (9Z)/18:1 (9Z))

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About This Item

经验公式(希尔记法):
C39H72O8PNa
分子量:
722.95
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

描述

1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 g (840875P-1g)
pkg of 2 × 100 mg (840875P-200mg)
pkg of 5 × 100 mg (840875P-500mg)
pkg of 1 × 25 mg (840875P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C39H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/b19-17-,20-18-;/t37-;/m1./s1

InChI key

JUKKLZHXFHPJSF-ZBFGHDQJSA-M

一般描述

18:1 PA (1,2-二油酰-sn-丙三醇-3-磷酸盐(钠盐))是阴离子脂质。

应用

18:1 PA (1,2-二油酰-sn-丙三醇-3-磷酸盐(钠盐)):
  • 可作为脂质体用于脂质体渗漏试验
  • 可用于创建脂质体模板,以便合成磷酸钙(CaP)纳米壳
  • 可用作脂质体/脂双层成分
  • 作为神经元神经胶质培养基添加剂,用于研究星形胶质细胞磷脂酶D1 (PLD1)对于树枝状分支的作用
  • 用于细胞色素c Trp59的化学发光试验

生化/生理作用

磷脂酸(PA)起脂质信使作用。

包装

5 mL 透明玻璃密封安瓿 (840875P-200 mg)
5 mL 透明玻璃密封安瓿 (840875P-25 mg)
5 mL 透明玻璃密封安瓿 (840875P-500 mg)
60 mL 琥珀色广口螺旋盖玻璃瓶 (840875P-1g)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Comparison of DOPA and DPPA liposome templates for the synthesis of calcium phosphate nanoshells
Yeo CH, et al.
Ceramics International, 38(1), 561-570 null
Xinhui Sun et al.
Cell cycle (Georgetown, Tex.), 14(5), 721-731 (2015-01-16)
It had been known for decades that primordial follicles in mammalian ovaries are assembled with definite numbers and represent the ovarian reserve throughout the reproductive life. Intra-oocyte PI3K/mTOR pathways have been indicated to play a central role on the activation
Shireesha Sankella et al.
The Journal of biological chemistry, 289(8), 4762-4777 (2014-01-16)
In this study we examined the role of phosphatidic acid (PA) in hepatic glucose production (HGP) and development of hepatic insulin resistance in mice that lack 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2). Liver lysophosphatidic acid and PA levels were increased ∼2- and
Shutao Guo et al.
Journal of controlled release : official journal of the Controlled Release Society, 174, 137-142 (2013-11-28)
The poor solubility of cisplatin (CDDP) often presents a major obstacle in the formulation of CDDP in nanoparticles (NPs) by traditional methods. We have developed a novel method for synthesizing CDDP NPs taking advantage of its poor solubility. By mixing
Kathleen Frondorf et al.
The Journal of biological chemistry, 285(21), 15837-15847 (2010-03-23)
Phosphatidic acid (PA) is a pleiotropic lipid second messenger in mammalian cells. We report here that extracellular PA acts as a leukocyte chemoattractant, as membrane-soluble dioleoyl-PA (DOPA) elicits actin polymerization and chemotaxis of human neutrophils and differentiated proleukemic HL-60 cells.

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