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安全信息

840857C

Avanti

16:0-18:1 PA

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt), chloroform

别名:

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); POPA; PA(16:0/18:1(9Z)); 110616

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About This Item

经验公式（希尔记法）:
C37H70O8PNa
CAS号:
169437-35-8
分子量:
696.91
MDL编号:
MFCD00672609
UNSPSC代码:
12352211
NACRES:
NA.25

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (840857C-25mg)
pkg of 2 × 4 mL (840857C-200mg)
pkg of 5 × 4 mL (840857C-500mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 840857C

浓度

10 mg/mL (840857C-25mg)
25 mg/mL (840857C-200mg)
25 mg/mL (840857C-500mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

InChI key

PPYXMAJBOKWTQX-RYRMQHSSSA-M

相关类别

一般描述

16:0-18:1 PA (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)/POPA) has eight oxygen atoms and one hydroxyl hydrogen atom. POPA is an anionic lipid.

应用

16:0-18:1 PA (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)) has been used to study its effects on the monogalactosyldiacylglycerol (MGDG) synthase activity of chloroplast envelope and in liposome Pull-Down Assay with the C2-like domain of SEIPIN.

生化/生理作用

Phosphatidic acid (PA) serves as a precursor for phosphatidylcholine or phosphatidylserine. It is involved in influencing the membrane curvature and signaling.

包装

5 mL Clear Glass Sealed Ampule (840857C-200mg)
5 mL Clear Glass Sealed Ampule (840857C-25mg)
5 mL Clear Glass Sealed Ampule (840857C-500mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

危险化学品
易制毒化学品（2类）

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分析证书(COA)

Lot/Batch Number

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Allison Dickey et al.
Biophysical journal, 95(6), 2636-2646 (2008-06-03)
To better understand bilayer property dependency on lipid electrostatics and headgroup size, we use atomistic molecular dynamics simulations to study negatively charged and neutral lipid membranes. We compare the negatively charged phosphatidic acid (PA), which at physiological pH and salt
Nadezhda Y Davydova et al.
The Biochemical journal, 476(23), 3661-3685 (2019-11-22)
In this study, we investigate the ability of ethanol-inducible CYP2E1 to interact with other cytochrome P450 species and affect the metabolism of their substrates. As a model system, we used CYP2E1-enriched human liver microsomes (HLM) obtained by the incorporation of
Bixia Zhang et al.
Plant physiology (2020-04-26)
Cinnamate 4-hydroxylase (C4H, CYP73A) is a cytochrome P450 monooxygenase associated externally with endoplasmic reticulum of plant cells. The enzyme uses NADPH-cytochrome P450 reductase (CPR) as a donor of electrons and hydroxylates cinnamic acid to form 4-coumaric acid in phenylpropanoid metabolism.
Renhong Yan et al.
Developmental cell, 47(2), 248-256 (2018-10-09)
The biogenesis of lipid droplets (LDs) and the development of adipocytes are two key aspects of mammalian fat storage. SEIPIN, an integral membrane protein of the endoplasmic reticulum (ER), plays a critical role in both LD formation and adipogenesis. The
Tingting Wang et al.
Frontiers in endocrinology, 9, 221-221 (2018-05-22)
Searching for nutraceuticals and understanding the underlying mechanism that promote fish growth is at high demand for aquaculture industry. In this study, the modulatory effects of soy phosphatidic acids (PA) on cell proliferation, nutrient sensing, and metabolic pathways were systematically
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