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检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 2.5 mL (840503C-25mg)
pkg of 2 × 4 mL (840503C-200mg)
制造商/商品名称
Avanti Polar Lipids 840503C
浓度
10 mg/mL (840503C-25mg)
25 mg/mL (840503C-200mg)
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
InChI
1S/C42H81O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,39-40,43-44H,3-17,19,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b20-18-;/t39?,40-;/m1./s1
InChI key
AZUBILBUHSANJX-VDVGXYCESA-M
一般描述
18:0-18:1 PG (SOPG/1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) is a hydrogenated phospholipid. It has two additional methylene groups in its saturated sn-1 chain. The thylakoid membranes of higher plants and cyanobacteria has phosphatidylglycerol (PG).
应用
18:0-18:1 PG (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used:
- as a component in biocompatible phospholipid bilayer to coat the gold nanoparticles (GNPs) surface
- in liposomes preparation
- in the formation of lipid monolayer
生化/生理作用
Phosphatidylglycerol (PG) helps to maintain the stability of photosystem I and II protein complexes. It is involved in bacterial defense mechanisms.
包装
5 mL Clear Glass Sealed Ampule (840503C-200mg)
5 mL Clear Glass Sealed Ampule (840503C-25mg)
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
靶器官
Liver,Kidney, Respiratory system
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
新产品
Jianjun Pan et al.
Biochimica et biophysica acta, 1818(9), 2135-2148 (2012-05-16)
We have determined the molecular structures of commonly used phosphatidylglycerols (PGs) in the commonly accepted biologically relevant fluid phase. This was done by simultaneously analyzing small angle neutron and X-ray scattering data, with the constraint of measured lipid volumes. We
J P Michel et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2967-2979 (2015-09-08)
Bacterial resistance to antibiotics has become today a major public health issue. In the development of new anti-infectious therapies, antimicrobial peptides appear as promising candidates. However, their mechanisms of action against bacterial membranes are still poorly understood. We describe for
Meijing Wang et al.
Biochimica et biophysica acta, 1831(6), 1089-1097 (2013-02-06)
Gold nanoparticles (GNPs) have been applied as diagnostic and therapeutic agents because they can be targeted, localized, and be heated to cause cell death. However, their use has been limited by their relatively low biocompatibility. In this work, we coated
J P Michel et al.
Langmuir : the ACS journal of surfaces and colloids, 33(41), 11028-11039 (2017-09-19)
The outer membrane (OM) of Gram-negative bacteria is a complex and asymmetric bilayer that antimicrobial peptides must disrupt in order to provoke the cell lysis. The inner and external leaflets of the OM are mainly composed of phospholipids (PL), and
Joury S van 't Klooster et al.
eLife, 9 (2020-04-18)
Yeast tolerates a low pH and high solvent concentrations. The permeability of the plasma membrane (PM) for small molecules is low and lateral diffusion of proteins is slow. These findings suggest a high degree of lipid order, which raises the
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