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安全信息

840475C

Avanti

18:1 (Δ9-Cis) PG

Avanti Research™ - A Croda Brand

别名:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))

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About This Item

经验公式（希尔记法）:
C42H78O10PNa
CAS号:
67254-28-8
分子量:
797.03
UNSPSC代码:
51191904
NACRES:
NA.25

描述

1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform solution

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (840475C-25mg)
pkg of 2 × 4 mL (840475C-200mg)
pkg of 5 × 4 mL (840475C-500mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

浓度

10 mg/mL (840475C-25mg)
25 mg/mL (840475C-200mg)
25 mg/mL (840475C-500mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

相关类别

一般描述

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.

应用


  • Probing the extended lipid anchorage with cytochrome c and liposomes containing diacylphosphatidylglycerol lipids.: This study investigates the interactions of cytochrome c with liposomes containing diacylphosphatidylglycerol (PG) lipids, including 18:1 (Δ9-Cis) PG. The research provides insights into the lipid anchorage and membrane dynamics, which are crucial for understanding cellular processes and developing biotechnological applications involving lipid-protein interactions (Abbott et al., 2018).

生化/生理作用

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

包装

5 mL Clear Glass Sealed Ampule (840475C-200mg)
5 mL Clear Glass Sealed Ampule (840475C-25mg)
5 mL Clear Glass Sealed Ampule (840475C-500mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

易制毒化学品（2类）
危险化学品

分析证书(COA)

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访问文档库

Lipids
Medical Biochemistry, 99- 119 (2017)
Membrane Structure and Dynamics
Cell Biology, 227- 239 (2017)
Md Zahidul Islam et al.
Langmuir : the ACS journal of surfaces and colloids, 33(9), 2433-2443 (2017-02-07)
The translocation of cell-penetrating peptides (CPPs) through plasma membranes of living cells is an important physiological phenomenon in biomembranes. To reveal the mechanism underlying the translocation of a CPP, transportan 10 (TP10), through lipid bilayers, we examined the effects of
Mariya Chavarha et al.
Biophysical journal, 104(3), 594-603 (2013-02-28)
The hydrophobic surfactant proteins, SP-B and SP-C, greatly accelerate the adsorption of the surfactant lipids to an air/water interface. Previous studies of factors that affect curvature suggest that vesicles may adsorb via a rate-limiting structure with prominent negative curvature, in
Alexandre M Almeida et al.
Langmuir : the ACS journal of surfaces and colloids, 35(51), 16745-16751 (2019-11-21)
The alarming increase in bacterial resistance to antibiotics has demanded new strategies for microbial inactivation, which include photodynamic therapy whose activity relies on the photoreaction damage to the microorganism membrane. Herein, the binding mechanisms of the photosensitizer toluidine blue-O (TBO)
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