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方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 25 mg (840419P-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 840419P
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OC)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C36H71O8P.Na/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-35(37)42-32-34(33-43-45(39,40)41-3)44-36(38)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2;/h34H,4-33H2,1-3H3,(H,39,40);/q;+1/p-1/t34-;/m1./s1
InChI key
JDEIVNUSWULHEB-MDYNBEAQSA-M
应用
16:0 Phosphatidylmethanol (1,2-dipalmitoyl-sn-glycero-3-phosphomethanol (sodium salt)) may be used as a standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) analysis for the quantification of phosphatidylethanols (PEths) in whole blood, venous/capillary-dried blood spots (V-DBS and C-DBS).
生化/生理作用
Phosphatidylmethanol is an anionic lipid which binds to the Phospholipase D. It is categorized as an alkyl phosphate lipid under headgroup modified lipids.
包装
5 mL Amber Glass Screw Cap Vial (840419P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
K Stieglitz et al.
The Journal of biological chemistry, 274(50), 35367-35374 (1999-12-10)
The Streptomyces chromofuscus phospholipase D (PLD) cleavage of phosphatidylcholine in bilayers can be enhanced by the addition of the product phosphatidic acid (PA). Other anionic lipids such as phosphatidylinositol, oleic acid, or phosphatidylmethanol do not activate this PLD. This allosteric
Natalie Kummer et al.
Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)
Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and
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