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检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 25 mg (840074P-25mg)
制造商/商品名称
Avanti Polar Lipids 840074P
脂质类型
phosphoglycerides
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
一般描述
磷脂酸（PA）是一种二酰基甘油磷脂，具有两个脂肪酸和一个磷酸盐，它们通过酯键共价连接到甘油分子上。通过内源酶磷脂酶D的活性或通过补充大豆卵磷脂来合成PA。
应用
大豆PA适用于研究其对细胞增殖，营养传感的效应以及检查大菱鲆（Scophthalmus maximus）原代肌肉细胞中的代谢途径。
生化/生理作用
磷脂酸（PA）是生物膜中存在的主要甘油磷脂，是磷脂酰胆碱或磷脂酰丝氨酸的前体。它在细胞中具有不同的功能，例如影响膜曲性和信号传导。
包装
5 mL透明玻璃密封安瓿（840074P-25mg）
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
The mitotic and metabolic effects of phosphatidic acid in the primary muscle cells of turbot (Scophthalmus maximus)
Wang T, et al.
Frontiers in Endocrinology, 9 (2018)
Phosphatidic acid enhances mTOR signaling and resistance exercise induced hypertrophy
Joy JM, et al.
Nutrition, 11(1), 29-29 (2014)
Daniel Schlam et al.
The Journal of biological chemistry, 288(32), 23090-23104 (2013-07-03)
It is commonly assumed that all phagosomes have identical molecular composition. This assumption has remained largely unchallenged due to a paucity of methods to distinguish individual phagosomes. We devised an assay that extends the utility of nitro blue tetrazolium for
Michal Bohdanowicz et al.
Molecular biology of the cell, 24(11), 1700-1712 (2013-04-12)
Macrophages and dendritic cells continuously survey their environment in search of foreign particles and soluble antigens. Such surveillance involves the ongoing extension of actin-rich protrusions and the consequent formation of phagosomes and macropinosomes. The signals inducing this constitutive cytoskeletal remodeling
Chi-Lun Chang et al.
The Journal of biological chemistry, 290(23), 14289-14301 (2015-04-19)
Phosphatidylinositol (PI) 4,5-bisphosphate (PIP2) at the plasma membrane (PM) constitutively controls many cellular functions, and its hydrolysis via receptor stimulation governs cell signaling. The PI transfer protein Nir2 is essential for replenishing PM PIP2 following receptor-induced hydrolysis, but key mechanistic
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