产品名称
大豆Lyso PC, Avanti Research™ - A Croda Brand 840072P, powder
SMILES string
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O
InChI
1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1
InChI key
ASWBNKHCZGQVJV-HSZRJFAPSA-N
assay
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
form
powder
packaging
pkg of 2 × 100 mg (840072P-200mg)
pkg of 1 × 25 mg (840072P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840072P
lipid type
phospholipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
Application
大豆Lyso PC已用于合成15-甲基十六烷酸（15-MHDA）和甘油磷脂。
Biochem/physiol Actions
大豆溶血磷酸胆碱或磷脂酰胆碱（PC）是大豆卵磷脂中存在的其他脂质之一。溶血磷脂酰胆碱（LPC）是一种具有生物活性的促炎脂质。它在病理活动中产生，并与动脉硬化症和炎症性疾病有关。LPC修饰多种细胞类型的功能，包括平滑肌细胞、内皮细胞、巨噬细胞、单核细胞和T细胞。LPC激活几个第二信使，并参与信号转导机制。
General description
溶血磷脂酰胆碱（LPC）或溶血卵磷脂是血浆（8-12%）和细胞膜（<3%）中的次要磷脂。
Packaging
5 mL透明玻璃密封安瓿（840072P-200mg）
5 mL透明玻璃密封安瓿（840072P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Lysophosphatidylcholine (lysolecithin) and its synthetic analogues. Immunemodulating and other biologic effects
Munder, PG and Modolell, M and Andreesen, Reinhard and Weltzien, HU and Westphal, O
Seminars in Immunopathology, 2(2), 187-203 (1979)
The use of natural and synthetic phospholipids as pharmaceutical excipients
van Hoogevest P and Wendel A
European Journal of Lipid Science and Technology, 116(9), 1088-1107 (2014)
Thomas Linemann et al.
Pharmaceutics, 5(2), 246-260 (2013-12-05)
The aim of the present study was to evaluate the transfection potential of chitosan-coated, green-fluorescent magnetic nanoparticles (MNPs) (chi-MNPs) after encapsulation inside polyethylglycol (PEG)ylated liposomes that produced lipid-encapsulated chitosan-coated MNPs (lip-MNPs), and also to evaluate how these particles would distribute
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Huynh K, et al.
Cell Chemical Biology, 26(1), 71-84 (2019)
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)
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