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安全信息

840064C

Avanti

18:0-20:4 PS

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

别名:

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); SAPS; PS(18:0/20:4(5Z,8Z,11Z,14Z)); 110673

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About This Item

经验公式（希尔记法）:
C44H77NO10PNa
CAS号:
474967-15-2
分子量:
834.05
UNSPSC代码:
12352211
NACRES:
NA.25

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (840064C-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 840064C

浓度

10 mg/mL (840064C-25mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C44H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-43(47)55-40(38-53-56(50,51)54-39-41(45)44(48)49)37-52-42(46)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2;/h11,13,17,19,22,24,28,30,40-41H,3-10,12,14-16,18,20-21,23,25-27,29,31-39,45H2,1-2H3,(H,48,49)(H,50,51);/q;+1/p-1/b13-11-,19-17-,24-22-,30-28-;/t40-,41+;/m1./s1

InChI key

PKENGTIYXZLXFZ-PTPAXTOESA-M

相关类别

一般描述

18:0-20:4 PS or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine is an asymmetric saturated-polyunsaturated phospholipid.

应用

18:0-20:4 PS or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt) has been used in the preparation of liposomes to study the effects of the fatty acid (FA) profile of phospholipids on membrane vesiculation by dynamin and endophilin.

包装

5 mL Clear Glass Sealed Ampule (840064C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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