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Merck
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文件

安全信息

840061C

Avanti

16:0-20:4 PS

1-palmitoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

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别名:
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PAPS; PS(16:0/20:4(5Z,8Z,11Z,14Z)); 110670
经验公式（希尔记法）:
C42H73NO10PNa
CAS号:
474943-16-3
分子量:
805.99
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 1 mL (840061C-10mg)

制造商/商品名称

Avanti Polar Lipids 840061C

浓度

10 mg/mL (840061C-10mg)

脂质类型

phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H74NO10P.Na/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-41(45)53-38(36-51-54(48,49)52-37-39(43)42(46)47)35-50-40(44)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2;/h11,13,17-18,20,22,26,28,38-39H,3-10,12,14-16,19,21,23-25,27,29-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b13-11-,18-17-,22-20-,28-26-;/t38-,39+;/m1./s1

InChI key

MMDGTLYKZWZGJV-ANGKXMAJSA-M

相关类别

一般描述

16:0-20:4 PS or 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine is a glycerophospholipid having, palmitic acid and arachidonic acid attached to the sn-1 and sn-2 positions of the glycerol backbone. The phospholipid in this compound is phosphoserine, a negatively charged lipid.

应用

16:0-20:4 PS or 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine has been used as a calibration standard for lipidomic analysis.

包装

5 mL Clear Glass Sealed Ampule (840061C-10mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

法规信息

危险化学品
易制毒化学品（2类）

分析证书(COA)

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Ségolène Hescot et al.
Oncotarget, 8(66), 109924-109940 (2018-01-05)
Mitotane (o,p'DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches as well as imaging analyses
Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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