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检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 25 mg (840055P-25mg)
制造商/商品名称
Avanti Polar Lipids 840055P
脂质类型
phosphoglycerides
phospholipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
一般描述
Phosphatidylcholine (PC) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH.
应用
Liver PC is suitable for use:
- as a standard for quantitation of tumor derived lipids by thin layer chromatography
- in the preparation of liposomes to mimic mammalian membranes
- in lipid vesicle preparation to study intravesicular transfer of α-tocopherol fluorescent derivative (NBD-Toc)
生化/生理作用
Phosphatidylcholine (PC) plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid. Liver PC has a saturated to unsaturated fatty acid ratio of 0.91.
包装
5 mL Clear Glass Sealed Ampule (840055P-25mg)
Noncovalently and covalently bound lipid on the receptor for immunoglobulin E
Kinet JP, et al.
Biochemistry, 24(25), 7342-7348 (1985)
Liposomes with diverse compositions are protected during desiccation by LEA proteins from Artemia franciscana and trehalose
Moore DS, et al.
Biochimica et Biophysica Acta - Biomembranes, 1858(1), 104-115 (2016)
Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein
Zhang WX, et al.
Lipids, 44(7), 631-631 (2009)
Essentials of Medical Biochemistry: With Clinical Cases (2011)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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