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Merck
CN

840053P

Avanti

Brain PC

Avanti Research - A Croda Brand 840053P, powder

别名:

L-α-phosphatidylcholine (Brain, Porcine)

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About This Item

UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 2 × 100 mg (840053P-200mg)
pkg of 1 × 25 mg (840053P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 840053P

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

一般描述

Phosphatidylcholine (PC) is an important structural component of cell membrane and plasma lipoprotein. It is synthesized by CDP choline pathway. Liver is the main site for the synthesis of PC. Brain PC predominantly contains PC 16:0/16:0 and PC 16:0/18:1.

应用

Brain PC is suitable for use:
  • in the preparation of small unilamellar vesicles (SUVs)
  • as a constituent in serial protein misfolding cyclic amplification (sPMCA) buffer
  • as standard for ion mobility shift-mass spectrometry (IMS-MS)

生化/生理作用

Phosphatidylcholine (PC) is the major source of choline through food supplements. PC helps in improving learning and memory. PC functions in membrane fusion and transport and endocytosis. It is implicated in lowering of blood lipid and cholesterol levels, preventing cardiovascular disease and inhibiting obesity.

包装

5 mL Clear Glass Sealed Ampule (840053P-200mg)
5 mL Clear Glass Sealed Ampule (840053P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


分析证书(COA)

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Choline, Phospholipids, Health, and Disease (1998)
The membrane lipid phosphatidylcholine is an unexpected source of triacylglycerol in the liver.
van der Veen JN, et al.
The Journal of Biological Chemistry, 287(28), 23418-23426 (2012)
Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine.
Zhou MM, et al.
Lipids in Health and Disease, 15(1), 135-135 (2016)
Requirements for mutant and wild-type prion protein misfolding in vitro.
Noble GP, et al.
Biochemistry, 54(5), 1180-1187 (2015)
Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins.
Methods in Cell Biology, 128, 223-241 (2015)

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