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检测方案
>99% (TLC)
形式
powder
包装
pkg of 2 × 100 mg (840052P-200mg)
pkg of 1 × 25 mg (840052P-25mg)
制造商/商品名称
Avanti Polar Lipids 840052P
脂质类型
phosphoglycerides
phospholipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChI key
JLPULHDHAOZNQI-ZTIMHPMXSA-N
一般描述
Contains ~40% plasmalogen ether lipid
Phosphatidylcholine (PC) is a glycerophospholipid present abundantly in eukaryotes. It comprises 40-50% of the total phospholipid content in the cell membrane. PC is synthesized by the Kennedy pathway.
应用
Heart PC has been used in the preparation of phospholipid reference mixture.
生化/生理作用
Phosphatidylcholine (PC) in the liver is responsible for the production of very low density lipoproteins (VLDL). It is an important source for the formation of lipid mediators and secondary messengers.
包装
5 mL Clear Glass Sealed Ampule (840052P-200mg)
5 mL Clear Glass Sealed Ampule (840052P-25mg)
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5(6), 16787-16787 (2015)
Expression of Shiga toxin 2e glycosphingolipid receptors of primary porcine brain endothelial cells and toxin-mediated breakdown of the blood-brain barrier
Meisen I, et al.
Glycobiology, 23(6), 745-759 (2013)
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.
van der Veen J N, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(9 Pt B), 1558-1558 (2017)
Marianne S Jurkowitz et al.
Biochimica et biophysica acta, 1848(2), 742-751 (2014-12-03)
Lysoplasmalogenase catalyzes hydrolytic cleavage of the vinyl-ether bond of lysoplasmalogen to yield fatty aldehyde and glycerophospho-ethanolamine or glycerophospho-choline. We recently purified lysoplasmalogenase from rat liver microsomes and identified the protein as TMEM86B, an integral membrane protein that is a member
Ivan U Kouzel et al.
Journal of lipid research, 54(3), 692-710 (2012-12-19)
Glycosphingolipids (GSLs) of the globo-series constitute specific receptors for Shiga toxins (Stxs) released by certain types of pathogenic Escherichia coli strains. Stx-loaded leukocytes may act as transporter cells in the blood and transfer the toxin to endothelial target cells. Therefore
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