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Merck
CN
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文件

840044P

Avanti

大豆 PI

Avanti Research™ - A Croda Brand

别名:

L-α-磷脂酰肌醇(大豆) （钠盐）

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About This Item

CAS号:
383907-36-6
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (840044P-10mg)
pkg of 2 × 100 mg (840044P-200mg)
pkg of 1 × 25 mg (840044P-25mg)
pkg of 1 × 50 mg (840044P-50mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1

InChI key

DCDQYHYLAGWAPO-UQZYTPKFSA-M

相关类别

一般描述

Lα-磷脂酰肌醇（大豆）是带负电荷的天然存在的带有肌醇环的甘油磷脂。它存在于生物膜中，参与支架、细胞区室化和信号转导。

应用

大豆PI已用于制备脂质体。

生化/生理作用

Lα-磷脂酰肌醇（大豆）在信号转导过程中起着细胞介质的关键作用。它用于设计药物递送的治疗性递送载体。大豆PI还有助于调节胆固醇代谢。

包装

5 mL透明玻璃密封安瓿（840044P-10mg）
5 mL透明玻璃密封安瓿（840044P-200mg）
5 mL透明玻璃密封安瓿（840044P-25mg）
5 mL透明玻璃密封安瓿（840044P-50mg）

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)
Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.
Sevova ES, et al.
The Journal of Biological Chemistry, 285(27), 20580-20587 (2010)
Yoshiko Uchiyama et al.
Brain research, 1151, 46-54 (2007-04-06)
Membrane composition serves to identify intracellular compartments, signal cell death, as well as to alter a cell's electrical and physical properties. Here we use amperometry to show that supplementation with the phospholipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), sphingomyelin (SM), and phosphatidylserine
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
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