描述
1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt)
检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 10 mg (840037P-10mg)
pkg of 1 × 200 mg (840037P-200mg)
pkg of 1 × 25 mg (840037P-25mg)
pkg of 1 × 500 mg (840037P-500mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1
InChI key
GTLXLANTBWYXGW-CEGNZRHUSA-M
一般描述
磷脂酰丝氨酸是一种在真核细胞中大量存在的阴离子磷脂。总细胞脂质的10％由磷脂酰丝氨酸组成。O-磷酸-L-丝氨酸是热稳定性底物。
应用
16：0 PS 已用于测定纯化动力学相关蛋白 1 (Drp1) 和合成脂质体之间互作的分析实验。
16：0 PS可用于脂质体浮选分析，用于测定其在纯化发动蛋白相关蛋白1（Drp1）之间的相互作用，并可作为制备单层脂质体的脂质混合物的成分。它还被用于通过脂膜水化法制备脂质体。
生化/生理作用
磷脂酰丝氨酸（PtdSer）参与各种细胞内信号通路。它还在细胞凋亡和血液凝固中起主要作用。
包装
20 mL 螺旋盖透明玻璃瓶 (840037P-200mg)
30 mL 螺旋盖棕色宽口瓶 (840037P-500mg)
5 mL 螺旋盖透明玻璃瓶 (840037P-10mg)
5 mL 螺旋盖透明玻璃瓶 (840037P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
Chelsea A Kraynak et al.
Acta biomaterialia, 108, 250-260 (2020-04-07)
Macrophages play a critical role in the initiation, maintenance, and resolution of inflammation because of their diverse and plastic phenotypic responses to extracellular stimuli. Inflammatory stimuli drive the recruitment and activation of inflammatory (M1) macrophages, capable of significant cytokine production
Ana Cristina Racca et al.
Frontiers in oncology, 9, 544-544 (2019-07-06)
Tumor cells require high rates of lipid synthesis to support membrane biogenesis for their exacerbated growth. The only two proteins known that activate phospholipid synthesis are Fra-1 and c-Fos, two members of the AP-1 family of transcription factors. These proteins
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
Bio-protocol, 7(9) (2017)
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