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Merck
CN

840035P

Avanti

18:1 PS (DOPS)

Avanti Research - A Croda Brand

别名:

1,2-二-(9Z-十八碳烯酰)--甘油基-3-磷酸-L-丝氨酸(钠盐);DOPS;PS (18:1 (9Z)/18:1 (9Z))

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About This Item

经验公式(希尔记法):
C42H77NO10PNa
CAS号:
分子量:
810.03
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (840035P-10mg)
pkg of 2 × 100 mg (840035P-200mg)
pkg of 5 × 100 mg (840035P-500mg)
pkg of 1 × 25 mg (840035P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand

溶解性

soluble (Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1

InChI key

KPHZNDUWYZIXFY-YORIBCANSA-M

一般描述

DOPS 是天然 Brain PS 的极好替代品。物理属性相似,对氧化较稳定。DOPS 已与 DOPC 和 DOPE 一起用于脂质混合物中,以模拟用于凝血研究的血小板膜。
磷酸丝氨酸/磷脂酰丝氨酸(PS)是一种内源性磷脂,存在于所有聚阴离子大分子中。

应用

18:1 PS/磷脂酰丝氨酸(DOPS)已用于:
  • 脂质体(多层囊泡)制备
  • 作为孵育缓冲液组分衡量外泌体相关促凝活性
  • 制备脂质囊泡

生化/生理作用

磷酸丝氨酸(PS)可用作识别癌症抗原125(CA 125)的模板。它对健康的神经细胞膜和髓磷脂至关重要。外源性PS可以被人体主动吸收。它具有穿越血脑屏障的能力。它在短时记忆形成、长时记忆巩固、新记忆建立等多种认知活动中起重要作用。它积极参与运动功能,例如快速反应和反射。

包装

5 mL 透明玻璃密封安瓿 (840035P-10 mg)
5 mL 透明玻璃密封安瓿 (840035P-200 mg)
5 mL 透明玻璃密封安瓿 (840035P-25 mg)
5 mL 透明玻璃密封安瓿 (840035P-500 mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

通常也和此产品一起购买

产品编号
说明
价格

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3


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Electrostatic interactions (EIs) play important roles in the structure and stability of inverse bicontinuous cubic (QII) phases of lipid membranes. We examined the effect of pH on the phase of dioleoylphosphatidylserine (DOPS)/monoolein (MO) membranes at low ionic strengths using small-angle
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