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安全和法规

840035C

Avanti

18:1 PS (DOPS)

Name: 18:1 PS (DOPS)
Brand: AVANTI

Avanti Research^™ - A Croda Brand

别名:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))

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About This Item

经验公式（希尔记法）:

C₄₂H₇₇NO₁₀PNa

CAS号:

90693-88-2

分子量:

810.03

UNSPSC代码:

51191904

NACRES:

NA.25

描述

1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 1 mL (840035C-10mg)
pkg of 1 × 2.5 mL (840035C-25mg)
pkg of 2 × 4 mL (840035C-200mg)
pkg of 5 × 4 mL (840035C-500mg)

制造商/商品名称

Avanti Research^™ - A Croda Brand

浓度

10 mg/mL (840035C-10mg)
10 mg/mL (840035C-25mg)
25 mg/mL (840035C-200mg)
25 mg/mL (840035C-500mg)

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1

InChI key

KPHZNDUWYZIXFY-YORIBCANSA-M

一般描述

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules. 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) carry a carboxylic acid group and a protonated amine group in their head group.

应用

18:1 PS (DOPS) has been used as a component of supported membrane tubes (SMrT) templates. It has also been used in the preparation of lipid-mixing vesicles, content-mixing vesicles and lipid mixture.

生化/生理作用

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

包装

30 mL Amber Narrow Mouth Bottle with Screw Cap (840035C-500mg)

5 mL Clear Glass Sealed Ampule (840035C-10mg)

5 mL Clear Glass Sealed Ampule (840035C-200mg)

5 mL Clear Glass Sealed Ampule (840035C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

通常也和此产品一起购买

产品编号

说明

价格

警示用语：

Danger

危险声明

H302,H315,H319,H331,H336,H351,H361d,H372,H412

预防措施声明

P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

危险化学品

易制毒化学品（2类）

分析证书(COA)

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A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins

Diao J, et al.

Nature Protocols, 7(5), 921-921 (2012)

Use of the supported membrane tube assay system for real time analysis of membrane fission reactions

Dar S, et al.

Nature Protocols, 12(2), 390-390 (2017)

Low-pH-Induced Lamellar to Bicontinuous Primitive Cubic Phase Transition in Dioleoylphosphatidylserine/Monoolein Membranes.

Toshihiko Oka et al.

Langmuir : the ACS journal of surfaces and colloids, 33(43), 12487-12496 (2017-10-03)

Electrostatic interactions (EIs) play important roles in the structure and stability of inverse bicontinuous cubic (QII) phases of lipid membranes. We examined the effect of pH on the phase of dioleoylphosphatidylserine (DOPS)/monoolein (MO) membranes at low ionic strengths using small-angle

Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment

Zhang Z, et al.

Biochimica et Biophysica Acta - Biomembranes, 1859(7), 1242- 1253 (2017)

Membrane Reconstitution of Monoamine Oxidase Enzymes on Supported Lipid Bilayers.

Liulin Wang et al.

Langmuir : the ACS journal of surfaces and colloids, 34(36), 10764-10773 (2018-07-28)

Monoamine oxidase A and B (MAO-A and B) are mitochondrial outer membrane enzymes that are implicated in a number of human diseases, and the pharmacological inhibition of these enzymes is a promising therapeutic strategy to alleviate disease symptoms. It has

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安全信息

18:1 PS (DOPS)

Avanti Research™ - A Croda Brand

About This Item

属性

描述

检测方案

形式

包装

制造商/商品名称

浓度

脂质类型

运输

储存温度

SMILES字符串

InChI

InChI key

相关类别

说明

一般描述

应用

生化/生理作用

包装

法律信息

相关产品

通常也和此产品一起购买

安全信息

象形图

警示用语：

危险声明

预防措施声明

危险分类

靶器官

储存分类代码

WGK

闪点(°F)

闪点(°C)

法规信息

文件

分析证书(COA)

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Avanti Research^™ - A Croda Brand