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Merck
CN

840032P

Avanti

脑 PS

Avanti Research - A Croda Brand

别名:

L-α-磷脂酰丝氨酸(大脑、猪)(钠盐)

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About This Item

UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (840032P-10mg)
pkg of 1 × 100 mg (840032P-100mg)
pkg of 5 × 100 mg (840032P-500mg)
pkg of 1 × 25 mg (840032P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

InChI key

ALPKKMIPHGSQRX-NJZWBUMZSA-M

应用

脑 PS 已用于脂质标准物质制备、 报告基因分析 和脂质体制备。

生化/生理作用

磷脂酰丝氨酸是一种脂质。它有助于提高大鼠和人类的认知能力,有不同程度的年龄依赖性记忆问题或可能的阿尔茨海默病。具有阻断老年大鼠基底前脑胆碱能神经元群变性的能力。 90% 的磷脂酰丝氨酸脱羧酶活性与线粒体相连。

包装

5 mL 透明玻璃密封安瓿 (840032P-10 mg)
5 mL 透明玻璃密封安瓿 (840032P-100 mg)
5 mL 透明玻璃密封安瓿 (840032P-25 mg)
5 mL 透明玻璃密封安瓿 (840032P-500 mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

通常也和此产品一起购买

储存分类代码

11 - Combustible Solids

WGK

WGK 3


分析证书(COA)

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访问文档库

Characterization of brain phosphatidylserine decarboxylase: localization in the mitochondrial inner membrane
Percy AK, et al.
Archives of Biochemistry and Biophysics, 223(2), 484-494 (1983)
Bovine brain phosphatidylserine attenuates scopolamine induced amnesia in mice
Claro FT, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 30(5), 881-886 (2006)
M Gangal et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(22), 12394-12399 (1999-10-27)
Although the catalytic (C) subunit of cAMP-dependent protein kinase is N-myristylated, it is a soluble protein, and no physiological role has been identified for its myristyl moiety. To determine whether the interaction of the two regulatory (R) subunit isoforms (R(I)
Measurement of Binding of Basic Drugs to Acidic Phospholipids using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-state Volume of Distribution (Vss)
Small H, et al.
Drug Metabolism and Disposition, dmd-111 (2011)
Molecular Medicines for Cancer: Concepts and Applications of Nanotechnology (2018)

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