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Merck
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文件

安全信息

840022C

Avanti

Brain PE

Avanti Polar Lipids 840022C

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别名:
L-α-phosphatidylethanolamine (Brain, Porcine)
CAS号:
383907-18-4
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (840022C-25mg)
pkg of 2 × 4 mL (840022C-200mg)

制造商/商品名称

Avanti Polar Lipids 840022C

浓度

10 mg/mL (840022C-25mg)
25 mg/mL (840022C-200mg)

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C41H80NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h18,20,39H,3-17,19,21-38,42H2,1-2H3,(H,45,46)/b20-18-/t39-/m1/s1

InChI key

JQKOHRZNEOQNJE-DJEJVYNPSA-N

相关类别

一般描述

Contains ~50% plasmalogen ether lipid

应用

Brain PE has been used as a cofactor to support the replication of highly infectious prion protein (PrPSc). It has also been used for the preparation of liposomes.

包装

5 mL Clear Glass Sealed Ampule (840022C-200mg)
5 mL Clear Glass Sealed Ampule (840022C-25mg)

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产品编号
说明
价格

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

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Contrasting effects of two lipid cofactors of prion replication on the conformation of the prion protein
Srivastava S and Baskakov IV
Testing, 10(6), e0130283-e0130283 (2015)
Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein
Makarava N, et al.
Acta Neuropathologica Communications, 6(1), 92-92 (2018)
Arupratan Das et al.
Nature cell biology, 14(3), 304-310 (2012-02-22)
Lipid asymmetry at the plasma membrane is essential for such processes as cell polarity, cytokinesis and phagocytosis. Here we find that a lipid flippase complex, composed of Lem3, Dnf1 or Dnf2, has a role in the dynamic recycling of the
Gillian L Dornan et al.
Structure (London, England : 1993), 28(2), 145-156 (2019-12-14)
The class I phosphoinositide 3-kinases (PI3Ks) are key signaling enzymes composed of a heterodimer of a p110 catalytic subunit and a p85 regulatory subunit, with PI3K mutations being causative of multiple human diseases including cancer, primary immunodeficiencies, and developmental disorders.
Saurabh Srivastava et al.
PloS one, 10(6), e0130283-e0130283 (2015-06-20)
Recent studies introduced two experimental protocols for converting full-length recombinant prion protein (rPrP) purified from E.coli into the infectious prion state (PrPSc) with high infectivity titers. Both protocols employed protein misfolding cyclic amplification (PMCA) for generating PrPSc de novo, but
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