跳转至内容
Merck
CN
所有图片(3)

文件

安全信息

840012C

Avanti

Heart CA

Avanti Polar Lipids

登录查看公司和协议定价
所有图片(3)
别名:
Cardiolipin (Heart, Bovine) (sodium salt)
CAS号:
383907-10-6
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2 mL (840012C-50mg)
pkg of 1 × 2.5 mL (840012C-25mg)
pkg of 1 × 4 mL (840012C-100mg)

制造商/商品名称

Avanti Polar Lipids

浓度

10 mg/mL (840012C-25mg)
25 mg/mL (840012C-100mg)
25 mg/mL (840012C-50mg)

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

InChI

1S/C81H142O17P2.2Na/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-61-65-78(83)91-71-76(97-80(85)67-63-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)73-95-99(87,88)93-69-75(82)70-94-100(89,90)96-74-77(98-81(86)68-64-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4)72-92-79(84)66-62-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2;;/h21-28,33-40,75-77,82H,5-20,29-32,41-74H2,1-4H3,(H,87,88)(H,89,90);;/q;2*+1/p-2/b25-21-,26-22-,27-23-,28-24-,37-33-,38-34-,39-35-,40-36-;;/t76-,77-;;/m1../s1

InChI key

ZGSPNIOCEDOHGS-LBOJVHLDSA-L

相关类别

一般描述

Cardiolipin is a phospholipid found in the inner membrane of the mitochondria. It is synthesized from phosphatidylglycerol and cytidinediphosphate-diacylglycerol. It consists of two phosphatidyl residues, which are linked by a glycerol group.

应用

Heart CA has been used in the Mycobacterium lipid extraction and in β- Hexosaminidase release and calcium mobilization assays. It maybe used for liposome synthesis. It may also be used as a lipid standard for the in situ analysis and characterization of cardiolipins.

生化/生理作用

Cardiolipin is involved in maintaining the structure and function of the mitochondria. It also serves as a co-factor for stimulating mitochondrial enzymes and mediates mitochondrial apoptosis. Cardiolipin is associated with the oxidative phosphorylation system for the adenine triphosphate (ATP) synthesis in the inner membrane of the mitochondria. Deficiency of cardiolipin is associated with variation of mitochondrial membrane structure and function. It is also associated with Barth syndrome.

包装

5 mL Clear Glass Sealed Ampule (840012C-100mg)
5 mL Clear Glass Sealed Ampule (840012C-25mg)
5 mL Clear Glass Sealed Ampule (840012C-50mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

易制毒化学品（2类）
危险化学品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Cardiolipin, the heart of mitochondrial metabolism
Houtkooper R H and Vaz F M
Cellular and Molecular Life Sciences, 65(16), 2493-2506 (2008)
Direct MALDI-MS analysis of cardiolipin from rat organs sections
Wang Hay-Yan J, et al.
Journal of the American Society For Mass Spectrometry, 18(3), 567-577 (2007)
Cardiolipin stabilizes respiratory chain supercomplexes
Pfeiffer K, et al.
The Journal of Biological Chemistry, 278(52), 52873-52880 (2003)
Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification
Cole NB, et al.
Experimental Cell Research, 314(10), 2076-2089 (2008)
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
Torres-Atencio I, et al.
American Journal of Respiratory and Critical Care Medicine, 198(6), 813-816 (2018)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门