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Merck
CN

830845P

Avanti

14:0 PA

1,2-dimyristoyl-sn-glycero-3-phosphate (sodium salt), powder

别名:

1,2-二十四烷酰基-sn-甘油-3-磷酸(钠盐);DMPA;PA(14:0/14:0)

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About This Item

经验公式(希尔记法):
C31H60O8PNa
CAS号:
分子量:
614.77
UNSPSC代码:
51191904
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 200 mg (830845P-200mg)
pkg of 1 × 25 mg (830845P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 830845P

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

InChI

1S/C31H61O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(32)37-27-29(28-38-40(34,35)36)39-31(33)26-24-22-20-18-16-14-12-10-8-6-4-2;/h29H,3-28H2,1-2H3,(H2,34,35,36);/q;+1/p-1/t29-;/m1./s1

InChI key

UBSPGYHFNIKQIP-XXIQNXCHSA-M

一般描述

磷脂酸是在磷脂酶D的帮助下从甘油磷脂获得的。14:0 PA/a带负电荷的1,2-二肉豆蔻酰基-sn-甘油-3-磷酸酯(DMPA)带有磷酸头基。

应用

14:0 PA可用于制备脂质体。它也可以用作磷脂(PL)标准品,以定量磷脂酸(PA)。

生化/生理作用

磷脂酸可用作吞噬细胞呼吸爆发的调节剂。它也是二酰基甘油和溶血磷脂酸的前体。

包装

5 mL棕色玻璃螺旋盖小瓶(830845P-200mg)
5 mL棕色玻璃螺旋盖小瓶(830845P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Although a minor component of the lipidome, phosphatidic acid (PA) plays a crucial role in nearly all signaling pathways involving cell membranes, in part because of its variable electrical charge in response to environmental conditions. To investigate how charge is
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The Journal of biological chemistry, 295(10), 2932-2947 (2020-01-26)
The δ isozyme of diacylglycerol kinase (DGKδ) plays critical roles in lipid signaling by converting diacylglycerol (DG) to phosphatidic acid (PA). We previously demonstrated that DGKδ preferably phosphorylates palmitic acid (16:0)- and/or palmitoleic acid (16:1)-containing DG molecular species, but not

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