检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (810298C-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810298C
浓度
1 mg/mL (810298C-1mg)
运输
dry ice
储存温度
−20°C
一般描述
Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs. LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.
应用
18:1-18:1-C11TopFluor™ TG (1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol) has been used as a standard to validate fluorescent lipid bands in fatty acid incorporation assay. It may also be used in fluorescent lipid synthesis.
包装
5 mL Clear Glass Sealed Ampule (810298C-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
危险化学品
易制毒化学品（2类）
Hanaa Hariri et al.
The Journal of cell biology, 218(4), 1319-1334 (2019-02-28)
Lipid droplets (LDs) serve as cytoplasmic reservoirs for energy-rich fatty acids (FAs) stored in the form of triacylglycerides (TAGs). During nutrient stress, yeast LDs cluster adjacent to the vacuole/lysosome, but how this LD accumulation is coordinated remains poorly understood. The
Øystein Sæle et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1863(9), 948-957 (2018-05-21)
The zebrafish larva is a powerful tool for the study of dietary triglyceride (TG) digestion and how fatty acids (FA) derived from dietary lipids are absorbed, metabolized and distributed to the body. While fluorescent FA analogues have enabled visualization of
Robert V Farese et al.
Cell, 139(5), 855-860 (2009-12-01)
Long underappreciated as important cellular organelles, lipid droplets are finally being recognized as dynamic structures with a complex and interesting biology. In light of this newfound respect, we discuss emerging views on lipid droplet biology and speculate on the major
Yuki Ohsaki et al.
The Journal of cell biology, 212(1), 29-38 (2016-01-06)
Lipid droplets (LDs) in the nucleus of hepatocyte-derived cell lines were found to be associated with premyelocytic leukemia (PML) nuclear bodies (NBs) and type I nucleoplasmic reticulum (NR) or the extension of the inner nuclear membrane. Knockdown of PML isoform
Robert V Farese et al.
The Journal of cell biology, 212(1), 7-8 (2016-01-06)
Lipid droplets (LDs) are sometimes found in the nucleus of some cells. In this issue, Ohsaki et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507122) show that the nuclear membrane, promyelocytic leukemia bodies, and the protein PML-II play a role in nuclear
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