810286C
Avanti
TopFluor® Cardiolipin
1,1′,2,2′-tetraoleoyl cardiolipin[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt) TopFluor® Cardiolipin, chloroform
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所有图片(1)
别名:
1′,3′-bis[1,2-dioleoyl-sn-glycero-3-phospho]-2′-[4-(dipyrrometheneboron difluoride) butanoyl]-sn-glycerol (ammonium salt); TopFluor-CL
经验公式（希尔记法）:
C98H175BF2N4O18P2
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检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (810286C-100ug)
pkg of 1 × 1 mL (810286C-500ug)
制造商/商品名称
Avanti Polar Lipids 810286C
浓度
0.1 mg/mL (810286C-100ug)
0.5 mg/mL (810286C-500ug)
运输
dry ice
储存温度
−20°C
一般描述
Cardiolipin, a unique phospholipid is present and synthesised in the inner mitochondrial membrane.
TopFluor® cardiolipin is a fluorescent analog of the bioactive phospholipid, cardiolipin.
生化/生理作用
Cardiolipin is very much essential for the functional activity of several inner mitochondrial membrane proteins, like respiratory chain complexes. It participates in mitochondrial oxidative phosphorylation. It is also essential for proper functioning and structure of the inner mitochondrial membrane (IMM).
包装
5 mL Amber Glass Screw Cap Vial (810286C-100ug)
5 mL Amber Glass Screw Cap Vial (810286C-500ug)
法律信息
TopFluor is a registered trademark of Avanti Polar Lipids, Inc.
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
危险化学品
易制毒化学品（2类）
Clyde A Daly et al.
Langmuir : the ACS journal of surfaces and colloids, 36(18), 5030-5039 (2020-04-18)
The composition, orientation, and conformation of proteins in biomolecular coronas acquired by nanoparticles in biological media contribute to how they are identified by a cell. While numerous studies have investigated protein composition in biomolecular coronas, relatively little detail is known
Functional role of cardiolipin in mitochondrial bioenergetics
Paradies G, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1837(4), 408-417 (2014)
Cintia Kawai et al.
The journal of physical chemistry. B, 118(41), 11863-11872 (2014-09-24)
Fluorescence quenching of lipid-bound pyrene was used to assess the binding of cytochrome c (cyt c) to liposomes that mimic the inner mitochondrial membrane (IMM) POPC/DOPE/TOCL, with the conditions that it did or did not contain oxidized phosphatidylcholine molecules, i.e.
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