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方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mL (810283C-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810283C
浓度
1 mg/mL (810283C-1mg)
运输
dry ice
储存温度
−20°C
一般描述
Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.
应用
TopFluor™ PS may be used in liposome generation and as a synthetic fluorescent PS analogue to study PS distribution and dynamics in mouse embryonic fibroblasts (MEFs). It has also been used to study the fluorescence resonance energy transfer (FRET) efficiency between TopFluor PtdSer and RFP-K-RasG12V PBD mutants and to directly measure its interaction with RFP-K-RasG12V PBD mutant.
生化/生理作用
Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It plays a key role in memory related issues and several other cognitive activities. PS actively participates in the locomotor functions. TopFluor-PS/1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phospho-l-serine is a synthetic fluorescent PS analog.
包装
5 mL Amber Glass Screw Cap Vial (810283C-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
Lipid-Sorting Specificity Encoded in K-Ras Membrane Anchor Regulates Signal Output
Zhou Y, et al.
Cell, 168(1), 239-251 (2017)
Phosphatidylserine dynamics in cellular membranes
Kay JG, et al.
Molecular Biology of the Cell, 23(11), 2198-2212 (2012)
Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Conrad KS, et al.
Nature Communications, 8(1908), 1-13 (2017)
Adsorption of O-phospho-L-serine and L-serine onto poorly crystalline apatite
Benaziz L, et al.
Journal of Colloid and Interface Science, 238(1), 48-53 (2001)
Phosphoserine imprinted nanosensor for detection of Cancer Antigen 125
Buyuktiryaki S, et al.
Talanta, 167, 172-180 (2017)
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