登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C39H58N4O5
化学文摘社编号:
分子量:
662.90
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
NBD-6 Cholesterol, Avanti Research™ - A Croda Brand 810251P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810251P-1mg)
pkg of 1 × 5 mg (810251P-5MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810251P
shipped in
dry ice
storage temp.
−20°C
Application
NBD-6 Cholesterol has been used for NBD-cholesterol binding assay, to study the binding of fluorescent NBD cholesterol in the binding pocket concerning ASTER domains.
Biochem/physiol Actions
Cholesterol is produced from acetyl-CoA by a complex multistep mevalonate pathway. In mammals, liver is the main site of de novo cholesterol synthesis contributing to almost 80% of total cholesterol synthesis. Cholesterol and its metabolites, along with its precursors, play important roles in cellular membrane physiology. They also have roles in reproductive biology, dietary nutrient absorption, stress responses, salt and water balance and calcium metabolism.
General description
NBD-6 Cholesterol is a fluorescent analog of the lipoprotein compound cholesterol, with NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) being the fluorescent group.
Packaging
5 mL Amber Glass Screw Cap Vial (810299P-1MG)
5 mL Amber Glass Screw Cap Vial (810251P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Fluorescent and Luminescent Probes for Biological Activity (1999)
Molecular Nutrition And Food Research, 277-290 (2016)
Pedro M R Cruz et al.
Frontiers in pharmacology, 4, 119-119 (2013-10-05)
While the unique metabolic activities of malignant tissues as potential targets for cancer therapeutics has been the subject of several recent reviews, the role of cholesterol metabolism in this context is yet to be fully explored. Cholesterol is an essential
Cholesterol in health and disease.
Ira Tabas
The Journal of clinical investigation, 110(5), 583-590 (2002-09-05)
Jaspreet Sandhu et al.
Cell, 175(2), 514-529 (2018-09-18)
The mechanisms underlying sterol transport in mammalian cells are poorly understood. In particular, how cholesterol internalized from HDL is made available to the cell for storage or modification is unknown. Here, we describe three ER-resident proteins (Aster-A, -B, -C) that
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持