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安全信息

810250C

Avanti

25-NBD 胆固醇

Avanti Research™ - A Croda Brand 810250C

别名:

25-[N-[(7-硝基-2-1,3-苯并恶二唑-4-基)甲基]氨基]-27-降胆甾醇

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About This Item

经验公式（希尔记法）:
C33H48N4O4
CAS号:
105539-27-3
分子量:
564.76
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 1 mL (810250C-10mg)
pkg of 1 × 1 mL (810250C-1mg)
pkg of 1 × 1 mL (810250C-5mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 810250C

浓度

1 mg/mL (810250C-1mg)
10 mg/mL (810250C-10mg)
5 mg/mL (810250C-5mg)

运输

dry ice

储存温度

−20°C

InChI

1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1

InChI key

RMGLSQAGXRZCPZ-OVHOIDCTSA-N

相关类别

一般描述

25-NBD胆固醇是胆固醇的荧光衍生物。其荧光特性是由于存在NBD（2-（4-硝基-2,1,3-苯并恶二唑-7-基）氨乙基）基团。

应用

25-NBD胆固醇可用作共聚焦显微镜的标记物，用于研究内体运输和囊泡形成。

生化/生理作用

胆固醇通过一系列酶促反应（称为甲羟戊酸途径）合成。胆固醇在质膜的结构和稳定性中起主要作用，并且还参与胆钙化醇（维生素D3）的合成。胆固醇在血管壁或动脉上聚积会导致血流阻塞，导致严重疾病动脉硬化。它是胆汁酸和类固醇激素（如孕酮、睾酮、皮质醇和醛固酮）合成的前体。

包装

5 mL透明玻璃密封安瓿 (810250C-10mg)
5 mL透明玻璃密封安瓿 (810250C-1mg)
5 mL透明玻璃密封安瓿 (810250C-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

危险化学品
易制毒化学品（2类）

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