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安全信息

810240P

Avanti

TopFluor® TMR PA

Avanti Polar Lipids 810240P, powder

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别名:
1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphate (ammonium salt)
经验公式(希尔记法):
C48H74 BF2N4 O10P
分子量:
946.90
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 1 mg (810240P-1mg)

制造商/商品名称

Avanti Polar Lipids 810240P

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidic acid (PA) is a diacyl-glycerophospholipid that consists of a glycerol and an alcohol moiety, having two fatty acids and a phosphate group esterified at positions 1, 2, and 3, respectively.

生化/生理作用

Phosphatidic acid (PA) is a signaling molecule that is synthesized in the endoplasmic reticulum (ER). It is transported to the mitochondrial outer membrane to stimulate mitofusin (Mfn)-mediated fusion. PA is a major intermediate metabolite involved in the synthesis of membrane glycerophospholipids, which include phosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and phosphatidylserine (PS).

包装

5 mL Amber Glass Screw Cap Vial (810240P-1mg)

法律信息

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

WGK

WGK 3

法规信息

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Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Multifunctional Systems for Combined Delivery Biosensing and Diagnostics, 28(1), 67-76 (2020)
Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders, 28(1), 67-76 (2015)
Shoichiro Kameoka et al.
Trends in cell biology, 28(1), 67-76 (2017-09-16)
Membrane organelles comprise both proteins and lipids. Remodeling of these membrane structures is controlled by interactions between specific proteins and lipids. Mitochondrial structure and function depend on regulated fusion and the division of both the outer and inner membranes. Here

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