检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 50 μg (810214P-50ug)
制造商/商品名称
Avanti Research™ - A Croda Brand 810214P
运输
dry ice
储存温度
−20°C
一般描述
C6-NBD Phytosphingosine is a fluorescent analog of the sphingoid compound, phytosphingosine with NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) being the fluorescent group. Phytosphingosine is specifically localised to tissues such as skin, kidney, and intestine in animals and decrease in its production may lead to disorders. Phytosphingosine (PHS) is a major a long-chain base in yeast and mammalian cells.
应用
C6-NBD Phytosphingosine N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-phytosphingosine is suitable to study membrane fusion with the help of fForster resonance energy transfer (FRET).
生化/生理作用
Phytosphingosine (PHS) is an important component of phytoceramides. PHS metabolism results in the production of sphingolipids and glycerophospholipids.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (810214P-50ug)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Fluorescent and Luminescent Probes for Biological Activity (1999)
Endotoxin-adsorbing macrophage-mimetic hybrid liposome for sepsis treatment
Jiang LL, et al.
Chemical Engineering Journal, 371(1), 15-25 (2019)
Hyun Kyung Choi et al.
Archives of dermatological research, 309(10), 795-803 (2017-09-25)
Phytosphingosine (PHS) is a sphingoid that is a key component of phytoceramides NP, AP and EOP. PHS has been known to have anti-inflammation and antimicrobial activities and to stimulate epidermal differentiation. In addition, it is reported that PHS treatment notably
Chunai Gong et al.
Journal of nanobiotechnology, 18(1), 92-92 (2020-06-18)
Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various membrane coatings, including membranes from specialized cells or hybrid membranes
Natsuki Kondo et al.
Nature communications, 5, 5338-5338 (2014-10-28)
The long-chain base phytosphingosine is a component of sphingolipids and exists in yeast, plants and some mammalian tissues. Phytosphingosine is unique in that it possesses an additional hydroxyl group compared with other long-chain bases. However, its metabolism is unknown. Here
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