所有图片(1)
别名:
N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-phytosphingosine
经验公式（希尔记法）:
C30H51N5O7
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检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (810214C-50ug)
制造商/商品名称
Avanti Polar Lipids 810214C
浓度
0.05 mg/mL (810214C-50ug)
运输
dry ice
储存温度
−20°C
一般描述
C6-NBD Phytosphingosine is a fluorescent derivative of phytosphingosine (PHS). Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.
应用
C6-NBD Phytosphingosine or N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-phytosphingosine is suitable for use in membrane fusion and verification studies using forster resonance energy transfer (FRET).
生化/生理作用
Phytosphingosine (PHS) is a long-chain base sphingoid and a major constituent of various phytoceramides. PHS is abundantly present in skin, intestine, and kidneys of animals. It exhibits anti-inflammatory and antimicrobial properties. PHS is known to increase the expression of genes including transglutaminase 1 and involucrin, that are involved in keratinocyte differentiation in humans.
包装
5 mL Amber Glass Screw Cap Vial (810214C-50ug)
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
易制毒化学品（2类）
危险化学品
Fluorescent and Luminescent Probes for Biological Activity null
Endotoxin-adsorbing macrophage-mimetic hybrid liposome for sepsis treatment
Jiang LL, et al.
Chemical Engineering Journal, 371(1), 15-25 (2019)
Hyun Kyung Choi et al.
Archives of dermatological research, 309(10), 795-803 (2017-09-25)
Phytosphingosine (PHS) is a sphingoid that is a key component of phytoceramides NP, AP and EOP. PHS has been known to have anti-inflammation and antimicrobial activities and to stimulate epidermal differentiation. In addition, it is reported that PHS treatment notably
Chunai Gong et al.
Journal of nanobiotechnology, 18(1), 92-92 (2020-06-18)
Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various membrane coatings, including membranes from specialized cells or hybrid membranes
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