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关于此项目
经验公式(希尔记法):
C42H73N6O13P
化学文摘社编号:
分子量:
901.04
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:1-12:0 NBD PS, Avanti Research™ - A Croda Brand 810195P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810195P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810195P
shipped in
dry ice
storage temp.
−20°C
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General description
磷脂酰丝氨酸(PS)是存在于人类大脑皮层中的酸性膜磷脂。它主要存在于质膜的内部小叶中。NBD PS包含在PS头基标记的荧光团7-硝基苯-2-氧杂-1,3-二氮杂-4-基(NBD)。
Application
18:1-12:0 NBD PS或1-油酰基-2-{12-[(7-硝基-2-1,3-苯并恶二唑-4-基)氨基]十二烷酰基}-sn-甘油-3-磷酸丝氨酸(铵盐)可用于测量磷脂酰丝氨酸脱羧酶(Psd1)活性。
Biochem/physiol Actions
磷脂酰丝氨酸(PS)参与维持神经细胞膜和髓鞘。磷脂酰丝氨酸(PS)与Akt、蛋白激酶C(PKC)和Raf-1信号传导有关。
Packaging
5 mL琥珀色玻璃螺旋盖小瓶(810195P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition null
Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R, et al.
Developmental Cell null
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids null
Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase
Yasunori W, et al.
Structure null
Jonathan R Friedman et al.
Developmental cell, 44(2), 261-270 (2018-01-02)
Spatial organization of phospholipid synthesis in eukaryotes is critical for cellular homeostasis. The synthesis of phosphatidylcholine (PC), the most abundant cellular phospholipid, occurs redundantly via the ER-localized Kennedy pathway and a pathway that traverses the ER and mitochondria via membrane
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